Trial · NCT02947269
Prucalopride in Postoperative Ileus
NCT02947269, Phase 3, Completed, University of Auckland, New Zealand
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Prucalopride in Postoperative Ileus. Trials, record NCT02947269. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02947269
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Prucalopride in Postoperative Ileus
- NCT number
- NCT02947269
- Status
- Completed
- Phases
- Phase 3
- Enrollment
- 150 participants, actual
- Lead sponsor
- University of Auckland, New Zealand
- Conditions
- Postoperative Ileus, Colorectal Surgery, Postoperative Complications
- Interventions
- Prucalopride, Placebo Oral Capsule
- First posted
- 2016-10-27
- Last updated
- 2021-09-29
Source ClinicalTrials.gov
Registered outcomes8
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Time until recovery of gastrointestinal function | From date of surgery until discharge from hospital (14 days on average) | Recovery of GI function is defined by the later time point (in days) of time to passage of stool AND time to tolerance of a solid or semi-solid diet. Patients will be reviewed twice per day using a structured questionnaire. |
| Secondary | Time until passage of stool (in days) | From date of surgery until discharge from hospital (14 days on average) | |
| Secondary | Time until passage of flatus (in days) | From date of surgery until discharge from hospital (14 days on average) | |
| Secondary | Time until tolerance of solid oral diet (in days) | From date of surgery until discharge from hospital (14 days on average) | |
| Secondary | Presence of prolonged postoperative ileus | From date of surgery until discharge from hospital (14 days on average) | Prolonged postoperative ileus is defined as presence of 2 or more of the following criteria on or after day 4 postoperatively: nausea or vomiting, inability to tolerate a solid or semi-solid oral diet, abdominal distension, absence of flatus and stool, radiological evidence of ileus. |
| Secondary | Levels of serum inflammatory markers (in pg/mL) | Inflammatory markers will be collected preoperatively, day 1 and 3 postoperatively. Blood samples will be stored after collection for later testing (up to 1 year). | Markers to be tested: CRP, IL1beta, IL6, IL8, IL12, TNFalpha |
| Secondary | Length of postoperative stay (in days) | From date of surgery until discharge from hospital (14 days on average) | |
| Other | Rate of gastric emptying using the 13-carbon octanoate breath test | This test will be undertaken on day 2 postoperatively, and will take approximately 4 hours | A subgroup of 40 patients will be investigated for this study |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 35639621 | DERIVED |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT02947269
GET https://conductscience.org/api/trials/v1/NCT02947269/registered