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Trial · NCT02957682

Results by group112

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Change From Baseline in Cambridge Neuropsychological Test Automated Battery (CANTAB) Cognitive Domain Spatial Working Memory (SWM) Strategy Z-Score at Week 96Placebo-0.180Standard Error 0.027Z-score
Change From Baseline in Cambridge Neuropsychological Test Automated Battery (CANTAB) Cognitive Domain Spatial Working Memory (SWM) Strategy Z-Score at Week 96Alirocumab 75 Q2W/Up150 Q2W-0.200Standard Error 0.027Z-score
Change From Baseline in CANTAB Cognitive Domain SWM Strategy Raw Score at Week 96Placebo-0.9Standard Deviation 4.49Units on a Scale
Change From Baseline in CANTAB Cognitive Domain SWM Strategy Raw Score at Week 96Alirocumab 75 Q2W/Up150 Q2W-1.0Standard Deviation 4.31Units on a Scale
Percent Change From Baseline in Calculated Low-density Lipoprotein Cholesterol (LDL-C) at Week 12, 24, 48, 72, and 96PlaceboPercent change at Week 120.6Standard Error 1.0Percent Change
Percent Change From Baseline in Calculated Low-density Lipoprotein Cholesterol (LDL-C) at Week 12, 24, 48, 72, and 96Alirocumab 75 Q2W/Up150 Q2WPercent change at Week 12-49.6Standard Error 0.9Percent Change
Percent Change From Baseline in Calculated Low-density Lipoprotein Cholesterol (LDL-C) at Week 12, 24, 48, 72, and 96PlaceboPercent change at Week 243.0Standard Error 1.0Percent Change
Percent Change From Baseline in Calculated Low-density Lipoprotein Cholesterol (LDL-C) at Week 12, 24, 48, 72, and 96Alirocumab 75 Q2W/Up150 Q2WPercent change at Week 24-54.2Standard Error 1.0Percent Change
Percent Change From Baseline in Calculated Low-density Lipoprotein Cholesterol (LDL-C) at Week 12, 24, 48, 72, and 96PlaceboPercent change at Week 482.8Standard Error 1.1Percent Change
Percent Change From Baseline in Calculated Low-density Lipoprotein Cholesterol (LDL-C) at Week 12, 24, 48, 72, and 96Alirocumab 75 Q2W/Up150 Q2WPercent change at Week 48-51.4Standard Error 1.1Percent Change
Percent Change From Baseline in Calculated Low-density Lipoprotein Cholesterol (LDL-C) at Week 12, 24, 48, 72, and 96PlaceboPercent change at Week 722.4Standard Error 1.2Percent Change
Percent Change From Baseline in Calculated Low-density Lipoprotein Cholesterol (LDL-C) at Week 12, 24, 48, 72, and 96Alirocumab 75 Q2W/Up150 Q2WPercent change at Week 72-50.4Standard Error 1.2Percent Change
Percent Change From Baseline in Calculated Low-density Lipoprotein Cholesterol (LDL-C) at Week 12, 24, 48, 72, and 96PlaceboPercent change at Week 964.0Standard Error 1.3Percent Change
Percent Change From Baseline in Calculated Low-density Lipoprotein Cholesterol (LDL-C) at Week 12, 24, 48, 72, and 96Alirocumab 75 Q2W/Up150 Q2WPercent change at Week 96-46.2Standard Error 1.3Percent Change
Percent Change From Baseline in Apolipoprotein (Apo) B at Week 12, 24, 48, 72, and 96PlaceboPercent change at Week 120.8Standard Error 0.7Percent Change
Percent Change From Baseline in Apolipoprotein (Apo) B at Week 12, 24, 48, 72, and 96Alirocumab 75 Q2W/Up150 Q2WPercent change at Week 12-36.7Standard Error 0.7Percent Change
Percent Change From Baseline in Apolipoprotein (Apo) B at Week 12, 24, 48, 72, and 96PlaceboPercent change at Week 242.1Standard Error 0.8Percent Change
Percent Change From Baseline in Apolipoprotein (Apo) B at Week 12, 24, 48, 72, and 96Alirocumab 75 Q2W/Up150 Q2WPercent change at Week 24-40.9Standard Error 0.8Percent Change
Percent Change From Baseline in Apolipoprotein (Apo) B at Week 12, 24, 48, 72, and 96PlaceboPercent change at Week 481.1Standard Error 0.8Percent Change
Percent Change From Baseline in Apolipoprotein (Apo) B at Week 12, 24, 48, 72, and 96Alirocumab 75 Q2W/Up150 Q2WPercent change at Week 48-39.0Standard Error 0.8Percent Change

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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