Trial · NCT02991937
Comparison of Medical and Surgical Treatment of Uncomplicated Acute Appendicitis in Children
NCT02991937, Phase 4, Completed, NYU Langone Health; results first posted 2022-01-21
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Comparison of Medical and Surgical Treatment of Uncomplicated Acute Appendicitis in Children. Trials, record NCT02991937. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT02991937
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Comparison of Medical and Surgical Treatment of Uncomplicated Acute Appendicitis in Children
- NCT number
- NCT02991937
- Status
- Completed
- Phases
- Phase 4
- Enrollment
- 39 participants, actual
- Lead sponsor
- NYU Langone Health
- Conditions
- Appendicitis
- Interventions
- Piperacillin/Tazobactam, Surgical Treatment
- First posted
- 2016-12-14
- Last updated
- 2022-01-21
- Results first posted
- 2022-01-21
Source ClinicalTrials.gov
Registered outcomes3
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Pediatric Quality of Life Inventory (PedsQL) Generic Core Scale - Parent | 1 Year | Brief, standardized, generic assessment instrument that systematically assesses patients' and parents' perceptions of health-related quality of life (HRQOL) in pediatric patients with chronic health conditions using pediatric cancer as an exemplary model. PedsQL consists of 23 items scored on a 5-point Likert scale (0=never to 4=almost always). Items are reversed scored and linearly transformed to a 0-100 scale (0=100, 1=75, 2=50, 3=25, and 4=0). The total score range is 0-100; the higher the score, the better the HRQOL. |
| Secondary | Readmission Rates | 1 Year | Percentage of patients readmitted to the hospital after discharge. |
| Secondary | Incidence of Long-term Complications in Medical Therapy Group | 1 Year | Incidence of long-term complications will be reported as number of cases where appendicitis reoccurred resulting in appendectomies in participants of the medical therapy arm. This data will be obtained from medical record review. |
Source ClinicalTrials.gov
Outcomes3
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Pediatric Quality of Life Inventory (PedsQL) Generic Core Scale - Parent | 1 Year | score on a scale | MEDIAN | |
| SECONDARY | Readmission Rates | 1 Year | percentage of participants | NUMBER | |
| SECONDARY | Incidence of Long-term Complications in Medical Therapy Group | 1 Year | Number of cases in 20 participants | NUMBER |
Source ClinicalTrials.gov
Results by group5
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Pediatric Quality of Life Inventory (PedsQL) Generic Core Scale - Parent | Medical Therapy | 91.3 | Inter-Quartile Range 82.6 to 98.9 | score on a scale | |
| Pediatric Quality of Life Inventory (PedsQL) Generic Core Scale - Parent | Surgical Intervention | 90.2 | Inter-Quartile Range 70.1 to 97.0 | score on a scale | |
| Readmission Rates | Medical Therapy | 25 | percentage of participants | ||
| Readmission Rates | Surgical Intervention | 0 | percentage of participants | ||
| Incidence of Long-term Complications in Medical Therapy Group | Medical Therapy | 30 | Number of cases in 20 participants |
Source ClinicalTrials.gov
Participant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Medical Therapy | 20 | |
| Overall Study | STARTED | Surgical Intervention | 19 | |
| Overall Study | COMPLETED | Medical Therapy | 20 | |
| Overall Study | COMPLETED | Surgical Intervention | 19 | |
| Overall Study | NOT COMPLETED | Medical Therapy | 0 | |
| Overall Study | NOT COMPLETED | Surgical Intervention | 0 |
Source ClinicalTrials.gov
Adverse events4
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events |
|---|---|---|---|---|---|---|
| other | Failure of Medical Therapy Requiring Surgery | Surgical and medical procedures | Medical Therapy | 6 | 20 | |
| other | Failure of Medical Therapy Requiring Surgery | Surgical and medical procedures | Surgical Intervention | 0 | 19 | |
| other | Readmission | Gastrointestinal disorders | Medical Therapy | 5 | 20 | |
| other | Readmission | Gastrointestinal disorders | Surgical Intervention | 0 | 19 |
Source ClinicalTrials.gov
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Medical Therapy | 0 | 20 |
| Total, all-cause mortality | Surgical Intervention | 0 | 19 |
| Total, other adverse events | Medical Therapy | 8 | 20 |
| Total, other adverse events | Surgical Intervention | 0 | 19 |
| Total, serious adverse events | Medical Therapy | 0 | 20 |
| Total, serious adverse events | Surgical Intervention | 0 | 19 |
Source ClinicalTrials.gov
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons2
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|---|
| Medical Therapy vs Surgical Intervention: deaths from any cause | Trial comparisons |
| Medical Therapy vs Surgical Intervention: serious adverse events | Trial comparisons |
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT02991937
GET https://conductscience.org/api/trials/v1/NCT02991937/registered