Trial · NCT03000413
Ketamine Efficacy for Acute Severe Bronchospasm in ICU: MACANUDO Trial
NCT03000413, Phase 2, Phase 3, Completed, Hospital Nossa Senhora da Conceicao
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Ketamine Efficacy for Acute Severe Bronchospasm in ICU: MACANUDO Trial. Trials, record NCT03000413. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03000413
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Ketamine Efficacy for Acute Severe Bronchospasm in ICU: MACANUDO Trial
- NCT number
- NCT03000413
- Status
- Completed
- Phases
- Phase 2, Phase 3
- Enrollment
- 45 participants, actual
- Lead sponsor
- Hospital Nossa Senhora da Conceicao
- Conditions
- Critical Illness, Asthma, Bronchospasm
- Interventions
- Ketamine, Fentanyl
- First posted
- 2016-12-22
- Last updated
- 2024-05-21
Source ClinicalTrials.gov
Registered outcomes7
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | bronchospasm improvement | 3 hours post beginning of drug infusion | Maximal airway resistance reduction in hour 3-post beginning of drug infusion |
| Secondary | bronchospasm improvement | 24 hours post beginning of drug infusion | Maximal airway resistance reduction in 24th hour post beginning of drug infusion |
| Secondary | Time to weaning | Time (in days) to first spontaneous breathing trial post randomization up to 28 days | Time (in days) to first spontaneous breathing trial post randomization up to 28 days |
| Other | Dynamic complacence improvement | 3 hours and 24 hours post beginning of drug infusion | |
| Other | Air trapping improvement | 3 hours and 24 hours post beginning of drug infusion | intrinsic PEEP reduction in 3 and 24h post beginning of drug infusion |
| Other | Heart rate | 3 hours and 24 hours post beginning of drug infusion | Heart rate in 3 hours and 24h post beginning of drug infusion |
| Other | Blood pressure | 3 hours and 24 hours post beginning of drug infusion | Blood pressure variation in 3 hours and 24hours post beginning of drug infusion |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers8
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT03000413
GET https://conductscience.org/api/trials/v1/NCT03000413/registered