Trial · NCT03005184
Mechanism(s) Underlying Cardiovascular Effects of ARB/NEP Inhibition - Aim 2
NCT03005184, Phase 2, Withdrawn, Vanderbilt University Medical Center
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Mechanism(s) Underlying Cardiovascular Effects of ARB/NEP Inhibition - Aim 2. Trials, record NCT03005184. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03005184
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Mechanism(s) Underlying Cardiovascular Effects of ARB/NEP Inhibition - Aim 2
- NCT number
- NCT03005184
- Status
- Withdrawn
- Phases
- Phase 2
- Enrollment
- 0 participants, actual
- Lead sponsor
- Vanderbilt University Medical Center
- Conditions
- Heart Failure NYHA Class I, Heart Failure NYHA Class II, Heart Failure NYHA Class III
- Interventions
- Valsartan 80 mg bid, Enalapril 10 mg bid, Sacubitril-Valsartan 200 mg bid, Icatibant, Placebo
- First posted
- 2016-12-29
- Last updated
- 2018-01-11
Source ClinicalTrials.gov
Registered outcomes13
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | change in systolic blood pressure | 7-hour period after 7-day intervention | |
| Primary | change in plasma cGMP | 7-hour period after 7-day intervention | |
| Secondary | heart rate | 7-hour period after 7-day intervention | |
| Secondary | renal plasma flow | 7-hour period after 7-day intervention | |
| Secondary | glomerular filtration rate | 7-hour period after 7-day intervention | |
| Secondary | change in diastolic blood pressure | 7-hour period after 7-day intervention | |
| Secondary | fractional excretion of sodium | 7-hour period after 7-day intervention | |
| Secondary | urine albumin-to-creatinine ratio | 7-hour period after 7-day intervention | |
| Secondary | brain natriuretic peptide (BNP) to N-terminal pro-BNP ratio | 7-hour period after 7-day intervention | |
| Secondary | plasminogen activator inhibitor-1 | 7-hour period after 7-day intervention |
1 to 10 of 13Source ClinicalTrials.gov
See all 13 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT03005184
GET https://conductscience.org/api/trials/v1/NCT03005184/registered