Trial · NCT03018834
Anakinra Versus Placebo for the Treatment of Acute MyocarditIS
NCT03018834, Phase 2, Phase 3, Completed, Assistance Publique - Hôpitaux de Paris
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Anakinra Versus Placebo for the Treatment of Acute MyocarditIS. Trials, record NCT03018834. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03018834
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Anakinra Versus Placebo for the Treatment of Acute MyocarditIS
- NCT number
- NCT03018834
- Status
- Completed
- Phases
- Phase 2, Phase 3
- Enrollment
- 120 participants, actual
- Lead sponsor
- Assistance Publique - Hôpitaux de Paris
- Conditions
- Acute Myocarditis
- Interventions
- ANAKINRA 100 mg/daily subcutaneously, Placebo
- First posted
- 2017-01-12
- Last updated
- 2024-03-06
- Other registries' IDs
- eudract:2016-003433-20
Source ClinicalTrials.gov
Registered outcomes15
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Number of days alive free of any myocarditis complications | within 28 days post hospitalization | Number of days alive free of any myocarditis complications defined as ventricular arrhythmias, heart failure, chest pain, ventricular dysfunction defined as LVEF\<50%, within 28 days post hospitalization |
| Secondary | Total cost | on average 14 days | Total cost |
| Secondary | Total Quality Adjusted Life Year (QALYs), | on average 14 days | measure of the perceived utility by patients of a medication (Anakinra) that corresponds to a year of life gained |
| Secondary | Incremental cost effectiveness | on average 14 days | cost-effectiveness of ANAKINRA in the setting of acute myocarditis |
| Secondary | Cost utility ratios | on average 14 days | Cost utility ratios |
| Secondary | Left Ventricul Ejection Fraction (LVEF) assessed by cardiac Magnetic Resonance Imaging (MRI) | at 6 month | Left Ventricul Ejection Fraction (LVEF) assessed by cardiac Magnetic Resonance Imaging (MRI) |
| Secondary | Left Ventricul Ejection Fraction (LVEF) assessed by Trans Thoracic Echocardiograhy (TTE) | at 6 month | Left Ventricul Ejection Fraction (LVEF) assessed by Trans Thoracic Echocardiograhy (TTE) |
| Secondary | LVEF assessed by cardiac MRI | at 1 year | LVEF assessed by cardiac MRI |
| Secondary | LVEF assessed by cardiac TTE | at 1 year | LVEF assessed by cardiac TTE |
| Secondary | All cause of death rate | during the 12 months follow-up | All cause of death rate |
1 to 10 of 15Source ClinicalTrials.gov
See all 15 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers2
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT03018834
GET https://conductscience.org/api/trials/v1/NCT03018834/registered