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Trial · NCT03031691

A Study of Brontictuzumab With Chemotherapy for Subjects With Previously Treated Metastatic Colorectal Cancer

NCT03031691, Phase 1, Completed, OncoMed Pharmaceuticals, Inc.

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. A Study of Brontictuzumab With Chemotherapy for Subjects With Previously Treated Metastatic Colorectal Cancer. Trials, record NCT03031691. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03031691

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
A Study of Brontictuzumab With Chemotherapy for Subjects With Previously Treated Metastatic Colorectal Cancer
NCT number
NCT03031691
Status
Completed
Phases
Phase 1
Enrollment
7 participants, actual
Lead sponsor
OncoMed Pharmaceuticals, Inc.
Conditions
Metastatic Colorectal Cancer
Interventions
brontictuzumab, trifluridine/tipiracil
First posted
2017-01-25
Last updated
2020-08-11

Source ClinicalTrials.gov

Registered outcomes7

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryPercentage of patients with adverse eventsup to approximately 2 years
PrimaryPercentage of patients with dose limiting toxicities28 days
PrimaryPercentage of patients with anti-brontictuzumab antibodiesup to approximately 2 years
SecondaryObjective Response according to Response Evaluation Criteria in Solid Tumors (RECIST 1.1)approximately 2 years
SecondaryProgression-free survival according to Response Evaluation Criteria in Solid Tumors (RECIST 1.1approximately 2 years
SecondaryChanges in number of circulating tumor cellsapproximately 2 years
SecondaryOverall survivalapproximately 2 years

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers0

The papers the trial lists on ClinicalTrials.gov.

None in this release.

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT03031691

GET https://conductscience.org/api/trials/v1/NCT03031691/registered