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Trial · NCT03033511

Results by group30

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Overall Survival (OS) in Participants With Extensive-Stage Small Cell Lung Cancer With Delta-Like Protein 3 High Expression in Tumor (DLL3high)Placebo9.7995% Confidence Interval 8.38 to 10.87months
Overall Survival (OS) in Participants With Extensive-Stage Small Cell Lung Cancer With Delta-Like Protein 3 High Expression in Tumor (DLL3high)Rovalpituzumab Tesirine/Dexamethasone8.4895% Confidence Interval 7.26 to 10.18months
OS in All Randomized ParticipantsPlacebo9.8995% Confidence Interval 8.61 to 11.01months
OS in All Randomized ParticipantsRovalpituzumab Tesirine/Dexamethasone8.8095% Confidence Interval 7.95 to 9.53months
Change From Baseline in European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core (EORTC QLQ-C30) Physical Functioning Domain Over TimePlaceboChange at Week 6-3.97Standard Error 1.00score on a scale
Change From Baseline in European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core (EORTC QLQ-C30) Physical Functioning Domain Over TimeRovalpituzumab Tesirine/DexamethasoneChange at Week 6-4.34Standard Error 0.95score on a scale
Change From Baseline in European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core (EORTC QLQ-C30) Physical Functioning Domain Over TimePlaceboChange at Week 12-1.70Standard Error 1.67score on a scale
Change From Baseline in European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core (EORTC QLQ-C30) Physical Functioning Domain Over TimeRovalpituzumab Tesirine/DexamethasoneChange at Week 12-12.13Standard Error 1.27score on a scale
Change From Baseline in European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core (EORTC QLQ-C30) Physical Functioning Domain Over TimePlaceboChange at Week 188.15Standard Error 4.02score on a scale
Change From Baseline in European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core (EORTC QLQ-C30) Physical Functioning Domain Over TimeRovalpituzumab Tesirine/DexamethasoneChange at Week 18-19.52Standard Error 4.92score on a scale
Change From Baseline in European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core (EORTC QLQ-C30) Physical Functioning Domain Over TimePlaceboChange at Week 24-0.95Standard Error 7.32score on a scale
Change From Baseline in European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core (EORTC QLQ-C30) Physical Functioning Domain Over TimeRovalpituzumab Tesirine/DexamethasoneChange at Week 24-19.39Standard Error 6.61score on a scale
Change From Baseline in European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core (EORTC QLQ-C30) Physical Functioning Domain Over TimePlaceboChange at Week 305.33Standard Error 4.22score on a scale
Change From Baseline in European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core (EORTC QLQ-C30) Physical Functioning Domain Over TimeRovalpituzumab Tesirine/DexamethasoneChange at Week 30-16.67Standard Error 6.78score on a scale
Change From Baseline in European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core (EORTC QLQ-C30) Physical Functioning Domain Over TimePlaceboChange at Week 36-13.33Standard Error NAscore on a scale
Change From Baseline in European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core (EORTC QLQ-C30) Physical Functioning Domain Over TimeRovalpituzumab Tesirine/DexamethasoneChange at Week 36-13.33Standard Error NAscore on a scale
Change From Baseline in European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core (EORTC QLQ-C30) Physical Functioning Domain Over TimePlaceboChange at Week 42-6.67Standard Error NAscore on a scale
Change From Baseline in European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core (EORTC QLQ-C30) Physical Functioning Domain Over TimeRovalpituzumab Tesirine/DexamethasoneChange at Week 42-3.33Standard Error NAscore on a scale
Change From Baseline in European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core (EORTC QLQ-C30) Physical Functioning Domain Over TimePlaceboChange at Week 48-6.67Standard Error NAscore on a scale
Change From Baseline in European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core (EORTC QLQ-C30) Physical Functioning Domain Over TimeRovalpituzumab Tesirine/DexamethasoneChange at Week 48-63.33Standard Error NAscore on a scale

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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