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Trial · NCT03049618

Outcomes20

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

TypeOutcomeTime framePopulationUnitsMeasured as
PRIMARYOverall Response Rate (ORR)Up to 22 monthsEvaluable population of patients who received at least 1 dose of therapy. No statistical analysis is performed.ParticipantsCOUNT_OF_PARTICIPANTS
SECONDARYDuration of ResponseUp to 22 monthsMonthsMEDIAN
SECONDARYNumber of Participants With Adverse EventsAdverse events were collected from first dose of study treatment up to 30 days after last dose of treatment, up to 21 months (number of treatment given ranged from 1 cycle to 30 cycles).All enrolled patients are included. No statistical analysis is performed.participantsNUMBER
SECONDARYOverall Survival (OS)Up to 41 monthsAll enrolled patients are included. Statistical analysis was not performed.MonthsMEDIAN
SECONDARYProgression Free Survival (PFS)Up to 23 monthsAll patients were included in the analysis. Statistical analysis was not performed.MonthsMEDIAN
OTHER_PRE_SPECIFIEDAssociation of Biomarker With Overall Response Rate - HPV StatusUp to 22 monthsOnly the Head and Neck cancer cohort is being reported. No specimens were collected for the non-small cell lung cancer cohort.ParticipantsCOUNT_OF_PARTICIPANTS
OTHER_PRE_SPECIFIEDAssociation of Biomarker With Overall Response Rate - P16 StatusUp to 22 monthsOnly the Head and Neck cancer cohort is being reported. No specimens were collected in the non-small cell lung cancer cohort.ParticipantsCOUNT_OF_PARTICIPANTS
OTHER_PRE_SPECIFIEDAssociation of Biomarkers With Overall Response Rate - EphrinB2 StatusUp to 22 monthsOnly the Head and Neck cancer cohort is being reported. No specimens were collected in the non-small cell lung cancer cohort.ParticipantsCOUNT_OF_PARTICIPANTS
OTHER_PRE_SPECIFIEDAssociation of Biomarkers With Overall Response Rate - PD-L1 StatusUp to 22 monthsOnly the Head and Neck cancer cohort is being reported. No specimens were collected in the non-small cell lung cancer cohort.ParticipantsCOUNT_OF_PARTICIPANTS
OTHER_PRE_SPECIFIEDAssociation of Biomarkers With Overall Response Rate - EphrinB2 Positive/HPV-negativeUp to 22 monthsOnly the Head and Neck cancer cohort is being reported. No statistical analysis performed. No specimens were collected in the non-small cell lung cancer cohort.ParticipantsCOUNT_OF_PARTICIPANTS
OTHER_PRE_SPECIFIEDAssociation of Biomarkers With Overall Survival (OS) - HPV StatusUp to 34 monthsOnly the Head and Neck cancer cohort is being reported. No specimens were collected in the non-small cell lung cancer cohort.MonthsMEDIAN
OTHER_PRE_SPECIFIEDAssociation of Biomarkers With Overall Survival (OS) - P16 StatusUp to 34 months
Only the Head and Neck cancer cohort is being reported. 10 participants were P16-positive, 15 participants were P16-negative, for a total of 25 participants. No specimens were collected in the non-small cell lung cancer cohort.
MonthsMEDIAN
OTHER_PRE_SPECIFIEDAssociation of Biomarkers With Overall Survival (OS) - EphrinB2Up to 24 monthsOnly the Head and Neck cancer cohort is being reported. No specimens were collected in the non-small cell lung cancer cohort.MonthsMEDIAN
OTHER_PRE_SPECIFIEDAssociation of Biomarkers With Overall Survival (OS) - PD-L1 StatusUp to 34 monthsOnly the Head and Neck cancer cohort is being reported. No specimens were collected in the non-small cell lung cancer cohort.MonthsMEDIAN
OTHER_PRE_SPECIFIEDAssociation of Biomarkers With Overall Survival (OS) - EphrinB2 Positive/HPV-negativeUp to 34 monthsOnly the Head and Neck cancer cohort is being reported. No statistical analysis performed. No specimens were collected in the non-small cell lung cancer cohort.MonthsMEDIAN
OTHER_PRE_SPECIFIEDAssociation of Biomarkers With Progression Free Survival (PFS) - HPV StatusUp to 11 monthsOnly the Head and Neck cancer cohort is being reported. No specimens were collected in the non-small cell lung cancer cohort.MonthsMEDIAN
OTHER_PRE_SPECIFIEDAssociation of Biomarkers With Progression Free Survival (PFS) - P16 StatusUp to 11 monthsOnly the Head and Neck cancer cohort is being reported. No specimens were collected in the non-small cell lung cancer cohort.MonthsMEDIAN
OTHER_PRE_SPECIFIEDAssociation of Biomarkers With Progression Free Survival (PFS) - EphrinB2 StatusUp to 11 monthsOnly the Head and Neck cancer cohort is being reported. No specimens were collected in the non-small cell lung cancer cohort.MonthsMEDIAN
OTHER_PRE_SPECIFIEDAssociation of Biomarkers With Progression Free Survival (PFS) - PD-L1 StatusUp to 11 monthsOnly the Head and Neck cancer cohort is being reported. No specimens were collected in the non-small cell lung cancer cohort.MonthsMEDIAN
OTHER_PRE_SPECIFIEDAssociation of Biomarkers With Progression Free Survival (PFS) - EphrinB2 Positive/HPV-negativeUp to 11 monthsOnly the Head and Neck cancer cohort is being reported. No statistical analysis performed. No specimens were collected in the non-small cell lung cancer cohort.MonthsMEDIAN

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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