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Trial · NCT03052608

Results by group576

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Progression-Free Survival (PFS) Based on Blinded Independent Central Review (BICR) AssessmentLorlatinibNA95% Confidence Interval NA to NAMonths
Progression-Free Survival (PFS) Based on Blinded Independent Central Review (BICR) AssessmentCrizotinib9.395% Confidence Interval 7.6 to 11.1Months
Overall Survival (OS)LorlatinibNA95% Confidence Interval NA to NAMonths
Overall Survival (OS)CrizotinibNA95% Confidence Interval NA to NAMonths
Progression-Free Survival (PFS) Based on Investigator's AssessmentLorlatinibNA95% Confidence Interval NA to NAMonths
Progression-Free Survival (PFS) Based on Investigator's AssessmentCrizotinib9.195% Confidence Interval 7.4 to 10.9Months
Objective Response Rate (ORR) - Percentage of Participants With Objective Response (OR) Based on BICR AssessmentLorlatinib75.895% Confidence Interval 68.2 to 82.5Percentage of participants
Objective Response Rate (ORR) - Percentage of Participants With Objective Response (OR) Based on BICR AssessmentCrizotinib57.895% Confidence Interval 49.4 to 65.9Percentage of participants
Objective Response Rate (ORR) - Percentage of Participants With Objective Response (OR) Based on Investigator's AssessmentLorlatinib80.595% Confidence Interval 73.3 to 86.6Percentage of participants
Objective Response Rate (ORR) - Percentage of Participants With Objective Response (OR) Based on Investigator's AssessmentCrizotinib61.995% Confidence Interval 53.5 to 69.8Percentage of participants
Intracranial Objective Response Rate (IC-ORR) - Percentage of Participants With Intracranial Objective Response (IC-OR) Based on BICR AssessmentLorlatinib65.895% Confidence Interval 48.6 to 80.4Percentage of participants
Intracranial Objective Response Rate (IC-ORR) - Percentage of Participants With Intracranial Objective Response (IC-OR) Based on BICR AssessmentCrizotinib20.095% Confidence Interval 9.1 to 35.6Percentage of participants
Intracranial Time to Progression (IC-TTP) Based on BICR AssessmentLorlatinibNA95% Confidence Interval NA to NAMonths
Intracranial Time to Progression (IC-TTP) Based on BICR AssessmentCrizotinib16.695% Confidence Interval 11.1 to NAMonths
Duration of Response (DR) Based on BICR AssessmentLorlatinibNA95% Confidence Interval NA to NAMonths
Duration of Response (DR) Based on BICR AssessmentCrizotinib11.095% Confidence Interval 9.0 to 12.9Months
Intracranial Duration of Response (IC-DR) Based on BICR AssessmentLorlatinibNA95% Confidence Interval NA to NAMonths
Intracranial Duration of Response (IC-DR) Based on BICR AssessmentCrizotinib9.495% Confidence Interval 6.0 to 11.1Months
Time to Tumor Response (TTR) Based on BICR AssessmentLorlatinib1.8Inter-Quartile Range 1.7 to 1.9Months
Time to Tumor Response (TTR) Based on BICR AssessmentCrizotinib1.8Inter-Quartile Range 1.7 to 1.9Months

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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