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Trial · NCT03057977

Results by group20

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Time to the First Event of Adjudicated Cardiovascular (CV) Death or Adjudicated Hospitalisation for Heart Failure (HHF)Placebo21.0095% Confidence Interval 19.13 to 22.96Patients with events/ 100 pt-yrs at risk
Time to the First Event of Adjudicated Cardiovascular (CV) Death or Adjudicated Hospitalisation for Heart Failure (HHF)10 mg Empagliflozin15.7795% Confidence Interval 14.19 to 17.44Patients with events/ 100 pt-yrs at risk
Occurrence of Adjudicated Hospitalisation for Heart Failure (HHF) (First and Recurrent)Placebo553HHF events
Occurrence of Adjudicated Hospitalisation for Heart Failure (HHF) (First and Recurrent)10 mg Empagliflozin388HHF events
eGFR (CKD-EPI) cr Slope of Change From BaselinePlacebo-2.278Standard Error 0.229Milliliter/minute/1.73 meters squared
eGFR (CKD-EPI) cr Slope of Change From Baseline10 mg Empagliflozin-0.546Standard Error 0.227Milliliter/minute/1.73 meters squared
Time to First Event in Composite Renal Endpoint: Chronic Dialysis, Renal Transplant or Sustained Reduction of eGFR(CKD-EPI)crPlacebo3.0795% Confidence Interval 2.33 to 3.91Patients with events/ 100 pt-yrs at risk
Time to First Event in Composite Renal Endpoint: Chronic Dialysis, Renal Transplant or Sustained Reduction of eGFR(CKD-EPI)cr10 mg Empagliflozin1.5695% Confidence Interval 1.06 to 2.17Patients with events/ 100 pt-yrs at risk
Time to First Adjudicated Hospitalisation for Heart Failure (HHF)Placebo15.5595% Confidence Interval 13.94 to 17.24Patients with events/ 100 pt-yrs at risk
Time to First Adjudicated Hospitalisation for Heart Failure (HHF)10 mg Empagliflozin10.7595% Confidence Interval 9.45 to 12.13Patients with events/ 100 pt-yrs at risk
Time to Adjudicated Cardiovascular (CV) DeathPlacebo8.1395% Confidence Interval 7.05 to 9.29Patients with events/ 100 pt-yrs at risk
Time to Adjudicated Cardiovascular (CV) Death10 mg Empagliflozin7.5595% Confidence Interval 6.51 to 8.67Patients with events/ 100 pt-yrs at risk
Time to All-cause MortalityPlacebo10.7195% Confidence Interval 9.46 to 12.04Patients with events/ 100 pt-yrs at risk
Time to All-cause Mortality10 mg Empagliflozin10.0695% Confidence Interval 8.85 to 11.34Patients with events/ 100 pt-yrs at risk
Time to Onset of Diabetes Mellitus (DM)Placebo10.6295% Confidence Interval 8.42 to 13.07Patients with events/ 100 pt-yrs at risk
Time to Onset of Diabetes Mellitus (DM)10 mg Empagliflozin9.3195% Confidence Interval 7.27 to 11.60Patients with events/ 100 pt-yrs at risk
Change From Baseline in KCCQ (Kansas City Cardiomyopathy Questionnaire) Clinical Summary Score at Week 52Placebo-3.36Standard Error 0.69Score on a scale
Change From Baseline in KCCQ (Kansas City Cardiomyopathy Questionnaire) Clinical Summary Score at Week 5210 mg Empagliflozin-1.30Standard Error 0.69Score on a scale
Number of All-cause Hospitalizations (First and Recurrent)Placebo1570Hospitalizations for any cause
Number of All-cause Hospitalizations (First and Recurrent)10 mg Empagliflozin1364Hospitalizations for any cause

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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