Trial · NCT03060473
Treatment of ppROM With Erythromycin vs. Azithromycin Trial
NCT03060473, Phase 3, Terminated, The University of Texas Medical Branch, Galveston; results first posted 2024-06-25
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Treatment of ppROM With Erythromycin vs. Azithromycin Trial. Trials, record NCT03060473. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03060473
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Treatment of ppROM With Erythromycin vs. Azithromycin Trial
- NCT number
- NCT03060473
- Status
- Terminated
- Phases
- Phase 3
- Enrollment
- 21 participants, actual
- Lead sponsor
- The University of Texas Medical Branch, Galveston
- Conditions
- Preterm Premature Rupture of Membranes (PPROM)
- Interventions
- Azithromycin, Erythromycin, Ampicillin, Amoxicillin
- First posted
- 2017-02-23
- Last updated
- 2024-06-25
- Results first posted
- 2024-06-25
- Limitations and caveats
- No data collected. The protocol was closed early due to low accrual and deemed futile.
Source ClinicalTrials.gov
Registered outcomes2
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Proportion of Women Still Pregnant by Day 7 | 7 days | Proportion of women still pregnant by day 7 after the diagnosis of PPROM is made. The investigators' working hypothesis is that there is no measurable difference in the primary outcome between the group randomized to the azithromycin regimen versus the group randomized to the erythromycin regimen |
| Secondary | Latency Defined as Interval From PPROM to Delivery. | 7 days | Number of days from diagnosis of PPROM to delivery |
Source ClinicalTrials.gov
Outcomes2
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Proportion of Women Still Pregnant by Day 7 | 7 days | No data collected. The protocol was closed early due to low accrual and deemed futile. | ||
| SECONDARY | Latency Defined as Interval From PPROM to Delivery. | 7 days | No data collected. The protocol was closed early due to low accrual and deemed futile. |
Source ClinicalTrials.gov
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Azithromycin | 11 | |
| Overall Study | STARTED | Erythromycin | 10 | |
| Overall Study | COMPLETED | Azithromycin | 11 | |
| Overall Study | COMPLETED | Erythromycin | 10 | |
| Overall Study | NOT COMPLETED | Azithromycin | 0 | |
| Overall Study | NOT COMPLETED | Erythromycin | 0 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Azithromycin | 0 | 0 |
| Total, all-cause mortality | Erythromycin | 0 | 0 |
| Total, other adverse events | Azithromycin | 0 | 0 |
| Total, other adverse events | Erythromycin | 0 | 0 |
| Total, serious adverse events | Azithromycin | 0 | 0 |
| Total, serious adverse events | Erythromycin | 0 | 0 |
Source ClinicalTrials.gov
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT03060473
GET https://conductscience.org/api/trials/v1/NCT03060473/registered