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Trial · NCT03061812

Results by group12

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Overall Survival (OS)Topotecan8.5795% Confidence Interval 7.69 to 10.12months
Overall Survival (OS)Rovalpituzumab Tesirine6.3495% Confidence Interval 5.55 to 7.33months
Progression Free Survival (PFS)Topotecan4.2795% Confidence Interval 3.75 to 5.42months
Progression Free Survival (PFS)Rovalpituzumab Tesirine3.0295% Confidence Interval 2.86 to 3.61months
Change From Baseline of the Physical Functioning Scale Score in European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 15-Palliative Care (EORTC QLQ-C15-PAL) at Week 7
Topotecan-7.1695% Confidence Interval -11.95 to -2.36score on a scale
Change From Baseline of the Physical Functioning Scale Score in European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 15-Palliative Care (EORTC QLQ-C15-PAL) at Week 7
Rovalpituzumab Tesirine-7.6695% Confidence Interval -11.31 to -4.01score on a scale
Objective Response Rate (ORR)Topotecan20.995% Confidence Interval 14.27 to 28.97percentage of participants
Objective Response Rate (ORR)Rovalpituzumab Tesirine14.695% Confidence Interval 10.75 to 19.26percentage of participants
Clinical Benefit Rate (CBR)Topotecan43.495% Confidence Interval 34.71 to 52.42percentage of participants
Clinical Benefit Rate (CBR)Rovalpituzumab Tesirine35.995% Confidence Interval 30.34 to 41.74percentage of participants
Duration of Objective Response (DOR)Topotecan4.8695% Confidence Interval 3.94 to 7.85months
Duration of Objective Response (DOR)Rovalpituzumab Tesirine3.5295% Confidence Interval 2.76 to 4.17months

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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