Trial · NCT03093246
Omega-3 Plus Low-dose Aspirin Daily Supplementation in Non-surgical Therapy to Treat Aggressive Periodontitis
NCT03093246, Phase 2, Phase 3, Completed, Universidade Estadual Paulista Júlio de Mesquita Filho; results first posted 2021-07-29
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Omega-3 Plus Low-dose Aspirin Daily Supplementation in Non-surgical Therapy to Treat Aggressive Periodontitis. Trials, record NCT03093246. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03093246
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Omega-3 Plus Low-dose Aspirin Daily Supplementation in Non-surgical Therapy to Treat Aggressive Periodontitis
- NCT number
- NCT03093246
- Status
- Completed
- Phases
- Phase 2, Phase 3
- Enrollment
- 38 participants, actual
- Lead sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
- Conditions
- Aggressive Periodontitis
- Interventions
- Omega-3 polyunsaturated fatty acids, Aspirin, Placebo, Full-mouth ultrasonic debridement
- First posted
- 2017-03-28
- Last updated
- 2021-12-28
- Results first posted
- 2021-07-29
Source ClinicalTrials.gov
Registered outcomes3
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in Probing Depth | Baseline, 3 and 6 months | Evaluate the difference between baseline and 6 months PD measures. |
| Secondary | Change in Clinical Attachment Level | Baseline, 3 and 6 months | Evaluate the difference between baseline and 6 months CAL measures. |
| Secondary | Change in Bleeding on Probe | Baseline, 3 and 6 months | Evaluate the difference between baseline and 6 months BoP measures |
Source ClinicalTrials.gov
Outcomes3
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Change in Probing Depth | Baseline, 3 and 6 months | milimeters | MEAN | |
| SECONDARY | Change in Clinical Attachment Level | Baseline, 3 and 6 months | milimeters | MEAN | |
| SECONDARY | Change in Bleeding on Probe | Baseline, 3 and 6 months | percentage of sites with BoP | MEAN |
Source ClinicalTrials.gov
Results by group18
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Change in Probing Depth | Control Group | Baseline | 3.88 | Standard Deviation 0.15 | milimeters |
| Change in Probing Depth | Test Group | Baseline | 3.74 | Standard Deviation 0.15 | milimeters |
| Change in Probing Depth | Control Group | 3 months | 3.38 | Standard Deviation 0.14 | milimeters |
| Change in Probing Depth | Test Group | 3 months | 3.26 | Standard Deviation 0.13 | milimeters |
| Change in Probing Depth | Control Group | 6 months | 3.37 | Standard Deviation 0.14 | milimeters |
| Change in Probing Depth | Test Group | 6 months | 3.25 | Standard Deviation 0.13 | milimeters |
| Change in Clinical Attachment Level | Control Group | Baseline | 3.94 | Standard Deviation 0.17 | milimeters |
| Change in Clinical Attachment Level | Test Group | Baseline | 4.01 | Standard Deviation 0.21 | milimeters |
| Change in Clinical Attachment Level | Control Group | 3 months | 3.58 | Standard Deviation 0.17 | milimeters |
| Change in Clinical Attachment Level | Test Group | 3 months | 3.65 | Standard Deviation 0.21 | milimeters |
1 to 10 of 18Source ClinicalTrials.gov
See all 18 results by groupParticipant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Control Group | 19 | |
| Overall Study | STARTED | Test Group | 19 | |
| Overall Study | COMPLETED | Control Group | 19 | |
| Overall Study | COMPLETED | Test Group | 19 | |
| Overall Study | NOT COMPLETED | Control Group | 0 | |
| Overall Study | NOT COMPLETED | Test Group | 0 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Control Group | 0 | 19 |
| Total, all-cause mortality | Test Group | 0 | 19 |
| Total, other adverse events | Control Group | 0 | 19 |
| Total, other adverse events | Test Group | 0 | 19 |
| Total, serious adverse events | Control Group | 0 | 19 |
| Total, serious adverse events | Test Group | 0 | 19 |
Source ClinicalTrials.gov
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 20572767 | BACKGROUND |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons2
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|---|
| Test Group vs Control Group: deaths from any cause | Trial comparisons |
| Test Group vs Control Group: serious adverse events | Trial comparisons |
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT03093246
GET https://conductscience.org/api/trials/v1/NCT03093246/registered