Trial · NCT03108352
Registered outcomes13
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
1 to 13 of 13
Download this page as JSON| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Best Corrected Visual Acuity | month 6 | Compare mean changes in Best Corrected Visual Acuity (BCVA) from baseline between the Conbercept ophthalmic injection treatment group (treatment group) and the control group at month 6. |
| Secondary | Best Corrected Visual Acuity (BCVA) | month 3 and month 12 | 1\>o evaluate mean changes in BCVA from baseline of the treatment group and the control group at month 3 and 12. |
| Secondary | Central Retinal Thickness | month 3, month 6 and month 12 | To evaluate mean changes in Central Retinal Thickness (CRT) from baseline of the treatment group and the control group at month 3, 6 and 12. |
| Secondary | resue treament | month 6 and month 12 | To evaluate the number of subjects who received laser rescue treatment of the treatment group and the control group at month 6 and 12. |
| Secondary | Number of participants with treatment-related the systemic and ocular safely as assessed | up to 12.5 months | To evaluate the systemic and ocular safety of the treatment group and the control group. |
| Secondary | distribution of BCVA changes | month 3, month 6 and month 12 | To evaluate the distribution of BCVA changes from baseline of the treatment group and the control group at month 3, 6 and 12. |
| Secondary | mean changes in BCVA | month 0,month 1,month 2,month 3,month 4,month 5,month 6,month 7,month 8,month 9,month 10,month 11 and month 12 | To evaluate mean changes in BCVA from baseline of the treatment group and the control group at every visit. |
| Secondary | Change in image | month 0,month 1,month 2,month 3,month 4,month 5,month 6,month 7,month 8,month 9,month 10,month 11 and month 12 | To evaluate the average changes in imaging findings (e.g., CRT and total macular volume) relative to the baseline for treatment group and control group at each follow-up visit. |
| Other | Immunogenic positive response in the treatment group | baseline,month 6, month 12 | Number of participants with Treatment-Ralated positive response to anti-drug antibody（ADA）or neutralizing antibody(Nab) in the treatment group at baseline,6 and 12months. |
| Other | Immunogenic positive response in the control group | baseline,month 6, month 12 | Number of participants with Treatment-Ralated positive response to anti-drug antibody（ADA）or neutralizing antibody(Nab) in thecontrol group at baseline,6 and 12months. |
| Other | safety analysis of immunogenic positive response | month 12 | To analyze the safely of subjects with positive response to ADA or Nab at 12 months after treatment and number of participants with positive respone who develop anticipants immuogenic adverse events. |
| Other | safety analysis of immunogenic negative response | month 12 | To analyze the safely of subjects with negative response to ADA or Nab at 12 months after treatment and number of participants with negative response who develop anticipants immuogenic adverse events. |
| Other | Best Corrected Visual Acuity (BCVA) | month 12 | To analyze the BCVA for subjects with positive response to ADA or Nab at 12 months after treatment. |
Source ClinicalTrials.govtrials-2026-11-12-0.4.0
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
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GET https://conductscience.org/api/trials/v1/NCT03108352/registered