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Trial · NCT03124368

Results by group87

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Change From Baseline In Serum C3 Complement Protein (C3) Levels On Day 15Group 1: Danicopan 100 mg TID (Sentinel)Baseline0.32Standard Deviation 0.060g/L
Change From Baseline In Serum C3 Complement Protein (C3) Levels On Day 15Group 2: Danicopan up to 200 mg TIDBaseline0.56Standard Deviation 0.230g/L
Change From Baseline In Serum C3 Complement Protein (C3) Levels On Day 15TotalBaseline0.48Standard Deviation 0.220g/L
Change From Baseline In Serum C3 Complement Protein (C3) Levels On Day 15Group 1: Danicopan 100 mg TID (Sentinel)Day 150.35Standard Deviation 0.060g/L
Change From Baseline In Serum C3 Complement Protein (C3) Levels On Day 15Group 2: Danicopan up to 200 mg TIDDay 150.70Standard Deviation 0.350g/L
Change From Baseline In Serum C3 Complement Protein (C3) Levels On Day 15TotalDay 150.58Standard Deviation 0.330g/L
Change From Baseline In Serum C3 Complement Protein (C3) Levels On Day 15Group 1: Danicopan 100 mg TID (Sentinel)Change from Baseline0.03Standard Deviation 0.000g/L
Change From Baseline In Serum C3 Complement Protein (C3) Levels On Day 15Group 2: Danicopan up to 200 mg TIDChange from Baseline0.14Standard Deviation 0.140g/L
Change From Baseline In Serum C3 Complement Protein (C3) Levels On Day 15TotalChange from Baseline0.11Standard Deviation 0.120g/L
Change From Baseline In Plasma Intact C3 Level On Day 15Group 1: Danicopan 100 mg TID (Sentinel)Baseline39.50Standard Deviation 0.710μg/mL
Change From Baseline In Plasma Intact C3 Level On Day 15Group 2: Danicopan up to 200 mg TIDBaseline58.25Standard Deviation 47.910μg/mL
Change From Baseline In Plasma Intact C3 Level On Day 15TotalBaseline52.00Standard Deviation 38.360μg/mL
Change From Baseline In Plasma Intact C3 Level On Day 15Group 1: Danicopan 100 mg TID (Sentinel)Day 1554.30Standard Deviation 17.390μg/mL
Change From Baseline In Plasma Intact C3 Level On Day 15Group 2: Danicopan up to 200 mg TIDDay 1533.50Standard Deviation 9.040μg/mL
Change From Baseline In Plasma Intact C3 Level On Day 15TotalDay 1540.43Standard Deviation 15.000μg/mL
Change From Baseline In Plasma Intact C3 Level On Day 15Group 1: Danicopan 100 mg TID (Sentinel)Change from Baseline14.80Standard Deviation 18.100μg/mL
Change From Baseline In Plasma Intact C3 Level On Day 15Group 2: Danicopan up to 200 mg TIDChange from Baseline-24.75Standard Deviation 50.970μg/mL
Change From Baseline In Plasma Intact C3 Level On Day 15TotalChange from Baseline-11.57Standard Deviation 45.180μg/mL
Change From Baseline In Total Complement Classical Pathway (CP) Activity On Day 14Group 1: Danicopan 100 mg TID (Sentinel)Baseline31.00Standard Deviation 21.210CAE unit
Change From Baseline In Total Complement Classical Pathway (CP) Activity On Day 14Group 2: Danicopan up to 200 mg TIDBaseline91.00Standard Deviation 41.370CAE unit

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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