Trial · NCT03131583
The Drug-Drug Interaction of SHR4640, Febuxostat and Colchicine in Patients With Gout
NCT03131583, Phase 1, Completed, Jiangsu HengRui Medicine Co., Ltd.
3 sourcestrials-2026-11-12-0.4.0
Cite this record
ConductScience Library. The Drug-Drug Interaction of SHR4640, Febuxostat and Colchicine in Patients With Gout. Trials, record NCT03131583. Release trials-2026-11-12-0.4.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03131583
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- The Drug-Drug Interaction of SHR4640, Febuxostat and Colchicine in Patients With Gout
- NCT number
- NCT03131583
- Status
- Completed
- Phases
- Phase 1
- Enrollment
- 15 participants, actual
- Lead sponsor
- Jiangsu HengRui Medicine Co., Ltd.
- Conditions
- Gout
- Interventions
- Colchicine, Febuxostat, SHR4640
- First posted
- 2017-04-27
- Last updated
- 2019-08-08
Source ClinicalTrials.gov
Registered outcomes7
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Maximun observed concentration (Cmax) of Febuxostat and Colchicine from plasma | Clinical significant changes from baseline up to Day 8 | PK profile |
| Primary | Area under the concentration-time curve (AUC) of Febuxostat and Colchicine from plasma | Clinical significant changes from baseline up to Day 8 | PK profile |
| Primary | Apparent terminal half-life (t1/2) of Febuxostat and Colchicine from plasma | Clinical significant changes from baseline up to Day 8 | PK profile |
| Secondary | Incidence of Adverse events | Clinical significant changes from Day-14 up to Day 16 | Safety issue |
| Secondary | Changes in Laboratory Values | Clinical significant changes from Day-14 up to Day 16 | Safety issue |
| Secondary | Changes in Electrocardiogram | Clinical significant changes from Day-14 up to Day 16 | Safety issue |
| Secondary | Changes in Vital Signs Parameters | Clinical significant changes from Day-14 up to Day 16 | Safety issue |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Source
- Release
- trials-2026-11-12-0.4.0
- Release manifest SHA-256
- 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4
- Registry capture
- 2026-11-12
- Results copy, AACT
- 2026-03-23
- NIH clinical studies file
- 2026-11-13
Source ClinicalTrials.gov
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNone stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT03131583
GET https://conductscience.org/api/trials/v1/NCT03131583/registered