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Trial · NCT03143153

Results by group35

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Overall Survival (OS) in Participants With Tumor Cell PD-L1Arm A: Nivolumab + Ipilimumab13.7095% Confidence Interval 11.24 to 17.02Months
Overall Survival (OS) in Participants With Tumor Cell PD-L1Arm B: Nivolumab + Chemotherapy15.4495% Confidence Interval 11.93 to 19.52Months
Overall Survival (OS) in Participants With Tumor Cell PD-L1Arm C: Chemotherapy9.0795% Confidence Interval 7.69 to 9.95Months
Progression-free Survival (PFS) as Assessed by BICR in Participants With Tumor Cell PD-L1Arm A: Nivolumab + Ipilimumab4.0495% Confidence Interval 2.40 to 4.93Months
Progression-free Survival (PFS) as Assessed by BICR in Participants With Tumor Cell PD-L1Arm B: Nivolumab + Chemotherapy6.9395% Confidence Interval 5.68 to 8.34Months
Progression-free Survival (PFS) as Assessed by BICR in Participants With Tumor Cell PD-L1Arm C: Chemotherapy4.4495% Confidence Interval 2.89 to 5.82Months
Overall Survival (OS) in All Randomized ParticipantsArm A: Nivolumab + Ipilimumab12.74795% Confidence Interval 11.269 to 15.474Months
Overall Survival (OS) in All Randomized ParticipantsArm B: Nivolumab + Chemotherapy13.20795% Confidence Interval 11.105 to 15.671Months
Overall Survival (OS) in All Randomized ParticipantsArm C: Chemotherapy10.71095% Confidence Interval 9.396 to 12.090Months
Progression-free Survival (PFS) in All Randomized Participants as Assessed by BICRArm A: Nivolumab + Ipilimumab2.89195% Confidence Interval 2.661 to 4.172Months
Progression-free Survival (PFS) in All Randomized Participants as Assessed by BICRArm B: Nivolumab + Chemotherapy5.78295% Confidence Interval 5.520 to 6.998Months
Progression-free Survival (PFS) in All Randomized Participants as Assessed by BICRArm C: Chemotherapy5.61895% Confidence Interval 4.304 to 5.914Months
Objective Response Rate (ORR) as Assessed by BICRArm A: Nivolumab + IpilimumabParticipants with baseline PD-L1 status < 1%20.195% Confidence Interval 14.3 to 27.1Percentage of participants
Objective Response Rate (ORR) as Assessed by BICRArm B: Nivolumab + ChemotherapyParticipants with baseline PD-L1 status < 1%41.795% Confidence Interval 34.1 to 49.7Percentage of participants
Objective Response Rate (ORR) as Assessed by BICRArm C: ChemotherapyParticipants with baseline PD-L1 status < 1%33.795% Confidence Interval 26.6 to 41.5Percentage of participants
Objective Response Rate (ORR) as Assessed by BICRArm A: Nivolumab + IpilimumabParticipants with baseline PD-L1 status >= 1%35.495% Confidence Interval 28.0 to 43.4Percentage of participants
Objective Response Rate (ORR) as Assessed by BICRArm B: Nivolumab + ChemotherapyParticipants with baseline PD-L1 status >= 1%53.295% Confidence Interval 45.1 to 61.1Percentage of participants
Objective Response Rate (ORR) as Assessed by BICRArm C: ChemotherapyParticipants with baseline PD-L1 status >= 1%19.995% Confidence Interval 13.9 to 27.0Percentage of participants
Objective Response Rate (ORR) as Assessed by BICRArm A: Nivolumab + IpilimumabParticipants with baseline PD-L1 status < 5%22.395% Confidence Interval 16.7 to 28.6Percentage of participants
Objective Response Rate (ORR) as Assessed by BICRArm B: Nivolumab + ChemotherapyParticipants with baseline PD-L1 status < 5%44.895% Confidence Interval 37.8 to 51.9Percentage of participants

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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