Trial · NCT03143751
Continuous Hyperosomolar Therapy for Traumatic Brain-injured Patients
NCT03143751, Phase 3, Completed, Nantes University Hospital
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Continuous Hyperosomolar Therapy for Traumatic Brain-injured Patients. Trials, record NCT03143751. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03143751
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Continuous Hyperosomolar Therapy for Traumatic Brain-injured Patients
- NCT number
- NCT03143751
- Status
- Completed
- Phases
- Phase 3
- Enrollment
- 370 participants, actual
- Lead sponsor
- Nantes University Hospital
- Conditions
- Moderate to Severe Traumatic Brain Injury
- Interventions
- NaCl20% (Continuous hyperosmolar therapy)
- First posted
- 2017-05-08
- Last updated
- 2020-12-08
Source ClinicalTrials.gov
Registered outcomes24
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Score on the Extended Glasgow Outcome Scale (GOS-E) at 6 months | 6 months | The GOS-E is a scale measuring the neurological recovery after traumatic brain injuries |
| Secondary | Mortality rate in ICU | 3 months | |
| Secondary | Mortality rate in ICU | 6 months | |
| Secondary | GOS-E | 3 months | The GOS-E is a scale measuring the neurological recovery after traumatic brain injuries |
| Secondary | functional independence measure : ADL (Activities of Daily Living) of Katz | 3 months | Scale measuring the autonomy of patient |
| Secondary | functional independence measure : ADL (Activities of Daily Living) of Katz | 6 months | Scale measuring the autonomy of patient |
| Secondary | Short Form 36 | 3 months | Scale measuring the quality of life |
| Secondary | Short Form 36 | 6 months | Scale measuring the quality of life |
| Secondary | Rate of patients with anterograde amnesia | 3 months | |
| Secondary | Rate of patients with anterograde amnesia | 6 months |
1 to 10 of 24Source ClinicalTrials.gov
See all 24 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers3
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT03143751
GET https://conductscience.org/api/trials/v1/NCT03143751/registered?page=2