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Trial · NCT03158285

Results by group2,681

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Percentage of Participants Who Achieved an American College of Rheumatology (ACR) 20 Response at Week 24Placebo to Guselkumab 100 mg q4w32.9percentage of participants
Percentage of Participants Who Achieved an American College of Rheumatology (ACR) 20 Response at Week 24Guselkumab 100 mg q8w64.1percentage of participants
Percentage of Participants Who Achieved an American College of Rheumatology (ACR) 20 Response at Week 24Guselkumab 100 mg q4w63.7percentage of participants
Change From Baseline in Health Assessment Questionnaire-Disability Index (HAQ-DI) Score at Week 24Placebo to Guselkumab 100 mg q4w-0.130095% Confidence Interval -0.1912 to -0.0687units on a scale
Change From Baseline in Health Assessment Questionnaire-Disability Index (HAQ-DI) Score at Week 24Guselkumab 100 mg q8w-0.367295% Confidence Interval -0.4282 to -0.3062units on a scale
Change From Baseline in Health Assessment Questionnaire-Disability Index (HAQ-DI) Score at Week 24Guselkumab 100 mg q4w-0.400495% Confidence Interval -0.4617 to -0.3390units on a scale
Percentage of Participants Who Achieved an ACR 50 Response at Week 24Placebo to Guselkumab 100 mg q4w14.2percentage of participants
Percentage of Participants Who Achieved an ACR 50 Response at Week 24Guselkumab 100 mg q8w31.5percentage of participants
Percentage of Participants Who Achieved an ACR 50 Response at Week 24Guselkumab 100 mg q4w33.1percentage of participants
Percentage of Participants Who Achieved Psoriasis Response With IGA Score of 0 (Cleared) or 1 (Minimal) and >=2 Grade Reduction From Baseline at Week 24 Among Participants With >=3% BSA Psoriatic Involvement and IGA Score of >=2 (Mild) at Baseline
Placebo to Guselkumab 100 mg q4w19.1percentage of participants
Percentage of Participants Who Achieved Psoriasis Response With IGA Score of 0 (Cleared) or 1 (Minimal) and >=2 Grade Reduction From Baseline at Week 24 Among Participants With >=3% BSA Psoriatic Involvement and IGA Score of >=2 (Mild) at Baseline
Guselkumab 100 mg q8w70.5percentage of participants
Percentage of Participants Who Achieved Psoriasis Response With IGA Score of 0 (Cleared) or 1 (Minimal) and >=2 Grade Reduction From Baseline at Week 24 Among Participants With >=3% BSA Psoriatic Involvement and IGA Score of >=2 (Mild) at Baseline
Guselkumab 100 mg q4w68.5percentage of participants
Percentage of Participants Who Achieved an American College of Rheumatology (ACR) 20 Response at Week 16Placebo to Guselkumab 100 mg q4w33.7percentage of participants
Percentage of Participants Who Achieved an American College of Rheumatology (ACR) 20 Response at Week 16Guselkumab 100 mg q8w55.2percentage of participants
Percentage of Participants Who Achieved an American College of Rheumatology (ACR) 20 Response at Week 16Guselkumab 100 mg q4w55.9percentage of participants
Change From Baseline in Modified Van Der Heijde-Sharp (vdH-S) Score at Week 24Placebo to Guselkumab 100 mg q4w0.9595% Confidence Interval 0.61 to 1.29units on a scale
Change From Baseline in Modified Van Der Heijde-Sharp (vdH-S) Score at Week 24Guselkumab 100 mg q8w0.5295% Confidence Interval 0.18 to 0.86units on a scale
Change From Baseline in Modified Van Der Heijde-Sharp (vdH-S) Score at Week 24Guselkumab 100 mg q4w0.2995% Confidence Interval -0.05 to 0.63units on a scale
Percentage of Participants With Resolution of Enthesitis at Week 24 Among the Participants With Enthesitis at BaselinePlacebo to Guselkumab 100 mg q4w29.4percentage of participants
Percentage of Participants With Resolution of Enthesitis at Week 24 Among the Participants With Enthesitis at BaselineGuselkumab 100 mg q8w49.6percentage of participants

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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