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Trial · NCT03186261

Antibacterial Effect of Nano Silver Fluoride vs Chlorhexidine on Occlusal Carious Molars Treated With Partial Caries Removal Technique

NCT03186261, Phase 3, Completed, Cairo University; results first posted 2021-09-16

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Antibacterial Effect of Nano Silver Fluoride vs Chlorhexidine on Occlusal Carious Molars Treated With Partial Caries Removal Technique. Trials, record NCT03186261. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03186261

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Antibacterial Effect of Nano Silver Fluoride vs Chlorhexidine on Occlusal Carious Molars Treated With Partial Caries Removal Technique
NCT number
NCT03186261
Status
Completed
Phases
Phase 3
Enrollment
44 participants, actual
Lead sponsor
Cairo University
Conditions
Dental Caries
Interventions
Nano silver fluoride solution, Cavity Cleanser
First posted
2017-06-14
Last updated
2021-09-16
Results first posted
2021-09-16

Source ClinicalTrials.gov

Registered outcomes1

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryBacterial Count of Streptococus Mutans5 minutes on average between baseline and after application of the solutionDigital Colony Counter, Agar Diffusion test

Outcomes1

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

TypeOutcomeTime framePopulationUnitsMeasured as
PRIMARYBacterial Count of Streptococus Mutans5 minutes on average between baseline and after application of the solutionCFU/ml log10MEAN

Results by group4

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Bacterial Count of Streptococus MutansNano Silver Fluoride SolutionBaseline2.00Standard Deviation 0.33CFU/ml log10
Bacterial Count of Streptococus MutansCavity CleanserBaseline2.04Standard Deviation 0.23CFU/ml log10
Bacterial Count of Streptococus MutansNano Silver Fluoride SolutionAfter solution application1.12Standard Deviation 0.59CFU/ml log10
Bacterial Count of Streptococus MutansCavity CleanserAfter solution application1.05Standard Deviation 0.63CFU/ml log10

Participant flow6

How many started, completed or left each group, period by period.

PeriodMilestoneGroupParticipantsUnits counted
Overall StudySTARTEDNano Silver Fluoride Solution2222
Overall StudySTARTEDCavity Cleanser2222
Overall StudyCOMPLETEDNano Silver Fluoride Solution2222
Overall StudyCOMPLETEDCavity Cleanser2222
Overall StudyNOT COMPLETEDNano Silver Fluoride Solution00
Overall StudyNOT COMPLETEDCavity Cleanser00

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals6

The totals the trial posted for each group.

TotalGroupAffectedAt risk
Total, all-cause mortalityNano Silver Fluoride Solution022
Total, all-cause mortalityCavity Cleanser022
Total, other adverse eventsNano Silver Fluoride Solution022
Total, other adverse eventsCavity Cleanser022
Total, serious adverse eventsNano Silver Fluoride Solution022
Total, serious adverse eventsCavity Cleanser022

Papers1

The papers the trial lists on ClinicalTrials.gov.

PMIDListed as
27041900BACKGROUND

Source PubMed

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons2

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

ComparisonSource
Nano Silver Fluoride Solution vs Cavity Cleanser: deaths from any causeTrial comparisons
Nano Silver Fluoride Solution vs Cavity Cleanser: serious adverse eventsTrial comparisons

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT03186261

GET https://conductscience.org/api/trials/v1/NCT03186261/registered