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Trial · NCT03201445

Results by group36

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Percentage of Participants With a ≥ 50% Decrease From Baseline in Sperm Concentration at Week 13Filgotinib1.5percentage of participants
Percentage of Participants With a ≥ 50% Decrease From Baseline in Sperm Concentration at Week 13Placebo9.0percentage of participants
Percentage of Participants With a ≥ 50% Decrease From Baseline in Sperm Concentration at Week 26Filgotinib/DB Filgotinib (Responder)5.0percentage of participants
Percentage of Participants With a ≥ 50% Decrease From Baseline in Sperm Concentration at Week 26Filgotinib/OL Filgotinib (Nonresponder)0percentage of participants
Percentage of Participants With a ≥ 50% Decrease From Baseline in Sperm Concentration at Week 26Placebo/DB Placebo (Responder)7.9percentage of participants
Percentage of Participants With a ≥ 50% Decrease From Baseline in Sperm Concentration at Week 26Placebo/OL Filgotinib (Nonresponder)11.8percentage of participants
Change From Baseline in Sperm Total Motility at Week 13Filgotinib-0.395% Confidence Interval -1.6 to 1.7percentage of motile sperms
Change From Baseline in Sperm Total Motility at Week 13Placebo0.495% Confidence Interval -1.3 to 1.5percentage of motile sperms
Change From Baseline in Sperm Total Motility at Week 26Filgotinib/DB Filgotinib (Responder)-2.395% Confidence Interval -4.7 to -0.3percentage of motile sperms
Change From Baseline in Sperm Total Motility at Week 26Filgotinib/OL Filgotinib (Nonresponder)-1.595% Confidence Interval -5.8 to 2.6percentage of motile sperms
Change From Baseline in Sperm Total Motility at Week 26Placebo/DB Placebo (Responder)0.095% Confidence Interval -3.4 to 2.4percentage of motile sperms
Change From Baseline in Sperm Total Motility at Week 26Placebo/OL Filgotinib (Nonresponder)0.895% Confidence Interval -7.3 to 5.8percentage of motile sperms
Change From Baseline in Total Sperm Count at Week 13Filgotinib-11.695% Confidence Interval -19.8 to 9.7million sperm cells/ejaculate
Change From Baseline in Total Sperm Count at Week 13Placebo-9.595% Confidence Interval -23.8 to 0.6million sperm cells/ejaculate
Change From Baseline in Total Sperm Count at Week 26Filgotinib/DB Filgotinib (Responder)2.095% Confidence Interval -19.6 to 17.2million sperm cells/ejaculate
Change From Baseline in Total Sperm Count at Week 26Filgotinib/OL Filgotinib (Nonresponder)-4.695% Confidence Interval -42.3 to 18.3million sperm cells/ejaculate
Change From Baseline in Total Sperm Count at Week 26Placebo/DB Placebo (Responder)-4.195% Confidence Interval -39.8 to 15.9million sperm cells/ejaculate
Change From Baseline in Total Sperm Count at Week 26Placebo/OL Filgotinib (Nonresponder)12.795% Confidence Interval -61.4 to 40.8million sperm cells/ejaculate
Change From Baseline in Sperm Concentration at Week 13Filgotinib1.095% Confidence Interval -2.2 to 3.9million sperm cells/mL
Change From Baseline in Sperm Concentration at Week 13Placebo0.795% Confidence Interval -2.7 to 1.7million sperm cells/mL

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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