Trial · NCT03210337

A Phase2 of A-101 Topical Solution in Subjects With Common Warts

NCT03210337, Phase 2, Completed, Aclaris Therapeutics, Inc.; results first posted 2019-05-01

3 sourcestrials-2026-11-12-0.5.0

Cite this record

ConductScience Library. A Phase2 of A-101 Topical Solution in Subjects With Common Warts. Trials, record NCT03210337. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03210337

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title: A Phase2 of A-101 Topical Solution in Subjects With Common Warts
NCT number: NCT03210337
Status: Completed
Phases: Phase 2
Enrollment: 157 participants, actual
Lead sponsor: Aclaris Therapeutics, Inc.
Conditions: Common Wart
Interventions: A-101 Topical Solution, A-101 Vehicle Solution
First posted: 2017-07-06
Last updated: 2019-05-01
Results first posted: 2019-05-01

Source ClinicalTrials.gov

Registered outcomes1

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

List	Outcome	Time frame	Description
Primary	Mean Change in Physician's Wart Assessment Score From Baseline to Day 57	Day 57	Physician's Wart Assessment Grade Descriptor 0 Clear: No visible wart. No further treatment is indicated. 1. Near Clear: A visible wart that is less than 3 mm in maximal diameter (or length) 2. A visible wart ≥ 3 mm and \< 6 mm in maximal diameter (or length) 3. A visible wart ≥ 6 mm in maximal diameter (or length)

Source ClinicalTrials.gov

Outcomes1

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

Type	Outcome	Time frame	Population	Units	Measured as
PRIMARY	Mean Change in Physician's Wart Assessment Score From Baseline to Day 57	Day 57	PP	score on a scale (PWA)	MEAN

Source ClinicalTrials.gov

Results by group2

Each measurement the trial posted, group by group, in the words and numbers it posted.

Outcome	Group	Category	Value	Spread	Units
Mean Change in Physician's Wart Assessment Score From Baseline to Day 57	Active		-0.77	Standard Deviation 0.85	score on a scale (PWA)
Mean Change in Physician's Wart Assessment Score From Baseline to Day 57	Vehicle		-0.23	Standard Deviation 0.49	score on a scale (PWA)

Source ClinicalTrials.gov

Participant flow6

How many started, completed or left each group, period by period.

Period	Milestone	Group	Participants
Overall Study	STARTED	Active	78
Overall Study	STARTED	Vehicle	79
Overall Study	COMPLETED	Active	70
Overall Study	COMPLETED	Vehicle	74
Overall Study	NOT COMPLETED	Active	8
Overall Study	NOT COMPLETED	Vehicle	5

Source ClinicalTrials.gov

Adverse events116

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

Type	Event	Organ system	Group	Affected	At risk	Events
other	Abdominal Pain	Gastrointestinal disorders	Active	0	78	0
other	Abdominal Pain	Gastrointestinal disorders	Vehicle	1	79	1
other	Toothache	Gastrointestinal disorders	Active	0	78	0
other	Toothache	Gastrointestinal disorders	Vehicle	1	79	1
other	Vomiting	Gastrointestinal disorders	Active	0	78	0
other	Vomiting	Gastrointestinal disorders	Vehicle	1	79	1
other	Influenza like illness	General disorders	Active	1	78	1
other	Influenza like illness	General disorders	Vehicle	0	79	0
other	Pain	General disorders	Active	0	78	0
other	Pain	General disorders	Vehicle	1	79	1

1 to 10 of 116Source ClinicalTrials.gov

See all 116 adverse events

Adverse event totals6

The totals the trial posted for each group.

Total	Group	Affected	At risk
Total, all-cause mortality	Active	0	78
Total, all-cause mortality	Vehicle	0	79
Total, other adverse events	Active	31	78
Total, other adverse events	Vehicle	24	79
Total, serious adverse events	Active	3	78
Total, serious adverse events	Vehicle	1	79

Source ClinicalTrials.gov

Papers0

The papers the trial lists on ClinicalTrials.gov.

None in this release.

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons2

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

Comparison	Source
Active vs Vehicle: deaths from any cause	Trial comparisons
Active vs Vehicle: serious adverse events	Trial comparisons

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov: 2026-11-12; ClinicalTrials.gov
Results, from AACT: 2026-03-23; AACT
NIH grant links: 2026-11-13; NIH RePORTER

Sources 3

ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
ClinicalTrials.govNo license stated
NIH RePORTER's clinical studies and project filesPublic domain

Each source's terms

ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
ClinicalTrials.govnone stated
NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT03210337

GET https://conductscience.org/api/trials/v1/NCT03210337/events?page=2

API reference For AI assistants