Trial · NCT03211897
Olanzapine, Haloperidol, Ziprasidone, Midazolam for Acute Undifferentiated Agitation
NCT03211897, Completed, Hennepin Healthcare Research Institute
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Olanzapine, Haloperidol, Ziprasidone, Midazolam for Acute Undifferentiated Agitation. Trials, record NCT03211897. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03211897
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Olanzapine, Haloperidol, Ziprasidone, Midazolam for Acute Undifferentiated Agitation
- NCT number
- NCT03211897
- Status
- Completed
- Enrollment
- 737 participants, actual
- Lead sponsor
- Hennepin Healthcare Research Institute
- Conditions
- Agitation,Psychomotor
- Interventions
- Haloperidol Injection, Ziprasidone Injection, OLANZapine Injection, Midazolam injection
- First posted
- 2017-07-07
- Last updated
- 2018-03-16
Source ClinicalTrials.gov
Registered outcomes3
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | The primary outcome will be the mean difference in Altered Mental Status (AMS) score from baseline at 15 minutes post-administration for each study drugs. | 15 minutes | Patients score on a previously validated agitation scale called the AMSS ADDENDUM: The primary outcome for this study was changed prior to study initiation to the proportion of patients adequately sedated at 15 minutes (defined as AMSS \< 1). This addendum was methodologically necessary to account for the ordinal, non-normal distribution of this data. |
| Secondary | Time to adequate sedation | Within the 120 minutes post-medication administration | The time elapsed in minutes to achieve a score of \< 1 on a validated agitation scale called the AMSS |
| Secondary | Rescue Sedation | 1 hour | Proportion of patients requiring additional medication for sedation within 1 hour |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 29885904 | DERIVED |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT03211897
GET https://conductscience.org/api/trials/v1/NCT03211897/registered