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Trial · NCT03222609

Results by group32

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Percentage of Participants With ≥ 35% Reduction From Baseline in Spleen Volume at Week 24Navitoclax + Ruxolitinib (Cohort 1a)26.4795% Confidence Interval 12.88 to 44.36percentage of participants
Percentage of Participants With ≥ 35% Reduction From Baseline in Spleen Volume at Week 24Navitoclax + Ruxolitinib (Cohort 1b)21.9895% Confidence Interval 13.97 to 31.88percentage of participants
Percentage of Participants With ≥ 35% Reduction From Baseline in Spleen Volume at Week 24Navitoclax (Cohort 2)11.7695% Confidence Interval 3.30 to 27.45percentage of participants
Percentage of Participants With ≥ 35% Reduction From Baseline in Spleen Volume at Week 24Navitoclax + Ruxolitinib (Cohort 3)62.5095% Confidence Interval 43.69 to 78.90percentage of participants
Percentage of Participants Achieving ≥ 50% Reduction From Baseline in Total System Score (TSS) at Week 24Navitoclax + Ruxolitinib (Cohort 1a)20.5995% Confidence Interval 8.70 to 37.90percentage of participants
Percentage of Participants Achieving ≥ 50% Reduction From Baseline in Total System Score (TSS) at Week 24Navitoclax + Ruxolitinib (Cohort 1b)25.2795% Confidence Interval 16.75 to 35.47percentage of participants
Percentage of Participants Achieving ≥ 50% Reduction From Baseline in Total System Score (TSS) at Week 24Navitoclax (Cohort 2)8.8295% Confidence Interval 1.86 to 23.68percentage of participants
Percentage of Participants Achieving ≥ 50% Reduction From Baseline in Total System Score (TSS) at Week 24Navitoclax + Ruxolitinib (Cohort 3)34.3895% Confidence Interval 18.57 to 53.19percentage of participants
Percentage of Participants Achieving Anemia ResponseNavitoclax + Ruxolitinib (Cohort 1a)Baseline transfusion independent with Baseline HGB <10 g/dL28.5795% Confidence Interval 3.67 to 70.96percentage of participants
Percentage of Participants Achieving Anemia ResponseNavitoclax + Ruxolitinib (Cohort 1b)Baseline transfusion independent with Baseline HGB <10 g/dL23.6895% Confidence Interval 11.44 to 40.24percentage of participants
Percentage of Participants Achieving Anemia ResponseNavitoclax (Cohort 2)Baseline transfusion independent with Baseline HGB <10 g/dL52.9495% Confidence Interval 27.81 to 77.02percentage of participants
Percentage of Participants Achieving Anemia ResponseNavitoclax + Ruxolitinib (Cohort 3)Baseline transfusion independent with Baseline HGB <10 g/dL38.4695% Confidence Interval 13.86 to 68.42percentage of participants
Percentage of Participants Achieving Anemia ResponseNavitoclax + Ruxolitinib (Cohort 1a)Baseline transfusion dependent50.0095% Confidence Interval 6.76 to 93.24percentage of participants
Percentage of Participants Achieving Anemia ResponseNavitoclax + Ruxolitinib (Cohort 1b)Baseline transfusion dependent16.6795% Confidence Interval 2.09 to 48.41percentage of participants
Percentage of Participants Achieving Anemia ResponseNavitoclax (Cohort 2)Baseline transfusion dependent37.5095% Confidence Interval 8.52 to 75.51percentage of participants
Percentage of Participants Achieving Anemia ResponseNavitoclax + Ruxolitinib (Cohort 3)Baseline transfusion dependent10095% Confidence Interval 15.81 to 100.00percentage of participants
Percentage of Participants Achieving Anemia ResponseNavitoclax + Ruxolitinib (Cohort 1a)Overall36.3695% Confidence Interval 10.93 to 69.21percentage of participants
Percentage of Participants Achieving Anemia ResponseNavitoclax + Ruxolitinib (Cohort 1b)Overall22.0095% Confidence Interval 11.53 to 35.96percentage of participants
Percentage of Participants Achieving Anemia ResponseNavitoclax (Cohort 2)Overall48.0095% Confidence Interval 27.80 to 68.69percentage of participants
Percentage of Participants Achieving Anemia ResponseNavitoclax + Ruxolitinib (Cohort 3)Overall46.6795% Confidence Interval 21.27 to 73.41percentage of participants

Source ClinicalTrials.govtrials-2026-11-12-0.4.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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