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Trial · NCT03223272

Mechanisms of Refractory Hypertension (Reserpine)

NCT03223272, Phase 2, Completed, University of Alabama at Birmingham; results first posted 2021-11-30

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Mechanisms of Refractory Hypertension (Reserpine). Trials, record NCT03223272. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03223272

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Mechanisms of Refractory Hypertension (Reserpine)
NCT number
NCT03223272
Status
Completed
Phases
Phase 2
Enrollment
7 participants, actual
Lead sponsor
University of Alabama at Birmingham
Conditions
Refractory Hypertension
Interventions
Reserpine
First posted
2017-07-21
Last updated
2021-11-30
Results first posted
2021-11-30

Source ClinicalTrials.gov

Registered outcomes1

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryChange Ambulatory Systolic Blood PressureBaseline and 8 weeksTwenty-four hour ambulatory systolic blood pressure

Outcomes1

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

TypeOutcomeTime framePopulationUnitsMeasured as
PRIMARYChange Ambulatory Systolic Blood PressureBaseline and 8 weeksmmHgMEAN

Results by group1

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Change Ambulatory Systolic Blood PressureReserpine-29.3Standard Deviation 22.2mmHg

Participant flow3

How many started, completed or left each group, period by period.

PeriodMilestoneGroupParticipantsUnits counted
Overall StudySTARTEDReserpine7
Overall StudyCOMPLETEDReserpine6
Overall StudyNOT COMPLETEDReserpine1

Adverse events1

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

TypeEventOrgan systemGroupAffectedAt riskEvents
seriousNSTEMICardiac disordersReserpine171

Adverse event totals3

The totals the trial posted for each group.

TotalGroupAffectedAt risk
Total, all-cause mortalityReserpine07
Total, other adverse eventsReserpine07
Total, serious adverse eventsReserpine17

Papers0

The papers the trial lists on ClinicalTrials.gov.

None in this release.

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT03223272

GET https://conductscience.org/api/trials/v1/NCT03223272/registered