Trial · NCT03289351
Two Different Antibiotics Versus One Antibiotic for Pediatric Perforated Appendicitis
NCT03289351, Phase 4, Completed, Phoenix Children's Hospital; results first posted 2024-01-12
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Two Different Antibiotics Versus One Antibiotic for Pediatric Perforated Appendicitis. Trials, record NCT03289351. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03289351
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Two Different Antibiotics Versus One Antibiotic for Pediatric Perforated Appendicitis
- NCT number
- NCT03289351
- Status
- Completed
- Phases
- Phase 4
- Enrollment
- 162 participants, actual
- Lead sponsor
- Phoenix Children's Hospital
- Conditions
- Perforated Appendicitis, Postoperative Infection
- Interventions
- Piperacillin, Tazobactam Drug Combination
- First posted
- 2017-09-20
- Last updated
- 2024-01-12
- Results first posted
- 2024-01-12
Source ClinicalTrials.gov
Registered outcomes3
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Number of Participants With a Postoperative Intra-abdominal Abscess | 30 days | Intra-abdominal abscess documented by ultrasound or computerized tomography |
| Secondary | Number of Participants With Postoperative Surgical Site Infection | 30 days | surgical site infections including superficial port site infection |
| Secondary | Number of Participants With a Postoperative Readmission | 30 days | readmission within 30 days for any gastrointestinal complaints or infectious complications |
Source ClinicalTrials.gov
Outcomes3
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Number of Participants With a Postoperative Intra-abdominal Abscess | 30 days | Participants | COUNT_OF_PARTICIPANTS | |
| SECONDARY | Number of Participants With Postoperative Surgical Site Infection | 30 days | Participants | COUNT_OF_PARTICIPANTS | |
| SECONDARY | Number of Participants With a Postoperative Readmission | 30 days | Participants | COUNT_OF_PARTICIPANTS |
Source ClinicalTrials.gov
Results by group6
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Number of Participants With a Postoperative Intra-abdominal Abscess | 2-drug Therapy | 19 | Participants | ||
| Number of Participants With a Postoperative Intra-abdominal Abscess | 1-drug Therapy | 5 | Participants | ||
| Number of Participants With Postoperative Surgical Site Infection | 2-drug Therapy | 4 | Participants | ||
| Number of Participants With Postoperative Surgical Site Infection | 1-drug Therapy | 4 | Participants | ||
| Number of Participants With a Postoperative Readmission | 2-drug Therapy | 11 | Participants | ||
| Number of Participants With a Postoperative Readmission | 1-drug Therapy | 4 | Participants |
Source ClinicalTrials.gov
Participant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | 2-drug Therapy | 80 | |
| Overall Study | STARTED | 1-drug Therapy | 82 | |
| Overall Study | COMPLETED | 2-drug Therapy | 80 | |
| Overall Study | COMPLETED | 1-drug Therapy | 82 | |
| Overall Study | NOT COMPLETED | 2-drug Therapy | 0 | |
| Overall Study | NOT COMPLETED | 1-drug Therapy | 0 |
Source ClinicalTrials.gov
Adverse events2
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events |
|---|---|---|---|---|---|---|
| other | Perioperative Redness/Edema | Skin and subcutaneous tissue disorders | 2-drug Therapy | 1 | 80 | 1 |
| other | Perioperative Redness/Edema | Skin and subcutaneous tissue disorders | 1-drug Therapy | 0 | 82 | 0 |
Source ClinicalTrials.gov
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | 2-drug Therapy | 0 | 80 |
| Total, all-cause mortality | 1-drug Therapy | 0 | 82 |
| Total, other adverse events | 2-drug Therapy | 1 | 80 |
| Total, other adverse events | 1-drug Therapy | 0 | 82 |
| Total, serious adverse events | 2-drug Therapy | 0 | 80 |
| Total, serious adverse events | 1-drug Therapy | 0 | 82 |
Source ClinicalTrials.gov
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons5
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|---|
| 2-drug Therapy vs 1-drug Therapy: Number of Participants With a Postoperative Readmission | Trial comparisons |
| 2-drug Therapy vs 1-drug Therapy: Number of Participants With a Postoperative Intra-abdominal Abscess | Trial comparisons |
| 2-drug Therapy vs 1-drug Therapy: Number of Participants With Postoperative Surgical Site Infection | Trial comparisons |
| 2-drug Therapy vs 1-drug Therapy: deaths from any cause | Trial comparisons |
| 2-drug Therapy vs 1-drug Therapy: serious adverse events | Trial comparisons |
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT03289351
GET https://conductscience.org/api/trials/v1/NCT03289351/registered