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Trial · NCT03291821

DuoStim in Cases of PGT: Comparison of Embryo Quantity and Embryonic Quality Using MitoScore

NCT03291821, Not applicable, Completed, IVI Madrid

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. DuoStim in Cases of PGT: Comparison of Embryo Quantity and Embryonic Quality Using MitoScore. Trials, record NCT03291821. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03291821

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
DuoStim in Cases of PGT: Comparison of Embryo Quantity and Embryonic Quality Using MitoScore
NCT number
NCT03291821
Status
Completed
Phases
Not applicable
Enrollment
136 participants, actual
Lead sponsor
IVI Madrid
Conditions
Infertility, Female
Interventions
human menopausal gonadotropin, GnRH antagonist, GnRH analog, Trophectoderm biopsy, MitoScore, Intracytoplasmic sperm injection, Ovarian puncture, Preimplantation genetic test, Embryo transfer, Pregnancy test, Embryo freezing, Embryo thawing
First posted
2017-09-25
Last updated
2020-12-29

Source ClinicalTrials.gov

Registered outcomes9

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryRate of euploid embryos per cycleup to 9 monthsRate of chromosomally normal embryos per cycle in the DuoStim group compared to the group undergoing two controlled ovarian hyperstimulation in consecutives cycles.
SecondaryNumber of oocytes obtainedup to 9 monthsTotal number of oocytes obtained in both arms after ovarian puncture
SecondaryNumber of fertilized oocytesup to 9 monthsNumber of fertilized oocytes in both arms after FIV/ICSI procedure
SecondaryNumber of biopsied blastocystsup to 9 monthsNumber of biopsied blastocysts in both arms
SecondaryMitoScore index of the euploid embryosup to 9 monthsAnalysis of the MitoScore index of the euploid embryos obtained in both arms
SecondaryImplantation rateup to 9 monthsImplantation rate of euploid embryos in both arms after single or double embryo transfer
SecondaryPregnancy rateup to 9 monthsPregnancy rate of euploid embryos in both arms after single or double embryo transfer
SecondaryAbortion rateup to 9 monthsAbortion rate presented by each arm after single or double embryo transfer
SecondaryTime until embryo transferup to 9 monthsPeriod elapsed from the beginning of the ovarian stimulation until the embryo transfer

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers12

The papers the trial lists on ClinicalTrials.gov.

PMIDListed asSource
12849812BACKGROUNDPubMed
18930226BACKGROUNDPubMed
20138269BACKGROUNDPubMed
20455017BACKGROUNDPubMed
21292255BACKGROUNDPubMed
23987516BACKGROUNDPubMed
24161646BACKGROUNDPubMed
25444501BACKGROUNDPubMed
25813280BACKGROUNDPubMed
25919235BACKGROUNDPubMed

1 to 10 of 12

See all 12 papers

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT03291821

GET https://conductscience.org/api/trials/v1/NCT03291821/registered