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A Study That Compares the Extent to Which Apomorphine Becomes Available in the Body After Taking Either an Investigational Drug Containing Apomorphine or Apomorphine That is Injected Under the Skin in People With PD Complicated by "OFF" Episodes
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Trial · NCT03292016

Results by group81

Each measurement the trial posted, group by group, in the words and numbers it posted.

61 to 80 of 81

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OutcomeGroupCategoryValueSpreadUnits
Terminal-phase Half-life (t½)APL-130277, Sublingual Thin FilmAPL 30 mg, APOKYN 5 mg and APO-go 5 mg1.21Geometric Coefficient of Variation 20.5h
Terminal-phase Half-life (t½)Subcutaneous APOKYNAPL 30 mg, APOKYN 5 mg and APO-go 5 mg0.89Geometric Coefficient of Variation 18.7h
Terminal-phase Half-life (t½)Subcutaneous APO-goAPL 30 mg, APOKYN 5 mg and APO-go 5 mg0.75Geometric Coefficient of Variation 35.5h
Terminal-phase Rate Constant ( λz)APL-130277, Sublingual Thin FilmAPL 20 mg, APOKYN 3 mg and APO-go 3 mg0.62Geometric Coefficient of Variation 15.6/h
Terminal-phase Rate Constant ( λz)Subcutaneous APOKYNAPL 20 mg, APOKYN 3 mg and APO-go 3 mg0.71Geometric Coefficient of Variation 9.9/h
Terminal-phase Rate Constant ( λz)Subcutaneous APO-goAPL 20 mg, APOKYN 3 mg and APO-go 3 mg0.80Geometric Coefficient of Variation 12.6/h
Terminal-phase Rate Constant ( λz)APL-130277, Sublingual Thin FilmAPL 25 mg, APOKYN 4 mg and APO-go 4 mg0.63Geometric Coefficient of Variation 34.3/h
Terminal-phase Rate Constant ( λz)Subcutaneous APOKYNAPL 25 mg, APOKYN 4 mg and APO-go 4 mg0.59Geometric Coefficient of Variation 20.6/h
Terminal-phase Rate Constant ( λz)Subcutaneous APO-goAPL 25 mg, APOKYN 4 mg and APO-go 4 mg0.68Geometric Coefficient of Variation 19.7/h
Terminal-phase Rate Constant ( λz)APL-130277, Sublingual Thin FilmAPL 30 mg, APOKYN 5 mg and APO-go 5 mg0.57Geometric Coefficient of Variation 20.5/h
Terminal-phase Rate Constant ( λz)Subcutaneous APOKYNAPL 30 mg, APOKYN 5 mg and APO-go 5 mg0.78Geometric Coefficient of Variation 18.7/h
Terminal-phase Rate Constant ( λz)Subcutaneous APO-goAPL 30 mg, APOKYN 5 mg and APO-go 5 mg0.92Geometric Coefficient of Variation 35.5/h
Metabolite/Parent (M/P) Drug Concentration Ratio -AUC LastAPL-130277, Sublingual Thin FilmAPL 20 mg, APOKYN 3 mg and APO-go 3 mg98.16Geometric Coefficient of Variation 6.4no unit
Metabolite/Parent (M/P) Drug Concentration Ratio -AUC LastSubcutaneous APOKYNAPL 20 mg, APOKYN 3 mg and APO-go 3 mg36.22Geometric Coefficient of Variation 3.0no unit
Metabolite/Parent (M/P) Drug Concentration Ratio -AUC LastSubcutaneous APO-goAPL 20 mg, APOKYN 3 mg and APO-go 3 mg32.19Geometric Coefficient of Variation 9.9no unit
Metabolite/Parent (M/P) Drug Concentration Ratio -AUC LastAPL-130277, Sublingual Thin FilmAPL 25 mg, APOKYN 4 mg and APO-go 4 mg45.79Geometric Coefficient of Variation 169.9no unit
Metabolite/Parent (M/P) Drug Concentration Ratio -AUC LastSubcutaneous APOKYNAPL 25 mg, APOKYN 4 mg and APO-go 4 mg18.70Geometric Coefficient of Variation 162.8no unit
Metabolite/Parent (M/P) Drug Concentration Ratio -AUC LastSubcutaneous APO-goAPL 25 mg, APOKYN 4 mg and APO-go 4 mg16.27Geometric Coefficient of Variation 221.6no unit
Metabolite/Parent (M/P) Drug Concentration Ratio -AUC LastAPL-130277, Sublingual Thin FilmAPL 30 mg, APOKYN 5 mg and APO-go 5 mg98.07Geometric Coefficient of Variation 55.4no unit
Metabolite/Parent (M/P) Drug Concentration Ratio -AUC LastSubcutaneous APOKYNAPL 30 mg, APOKYN 5 mg and APO-go 5 mg33.63Geometric Coefficient of Variation 6.2no unit

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

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Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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