Trial · NCT03304457
Lurasidone Vs Olanzapine on Neurotrophic Biomarkers and Cardiometabolic Parameters in Unmedicated Schizophrenia
NCT03304457, Phase 4, Completed, All India Institute of Medical Sciences, Bhubaneswar
3 sourcestrials-2026-11-12-0.4.0
Cite this record
ConductScience Library. Lurasidone Vs Olanzapine on Neurotrophic Biomarkers and Cardiometabolic Parameters in Unmedicated Schizophrenia. Trials, record NCT03304457. Release trials-2026-11-12-0.4.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03304457
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Lurasidone Vs Olanzapine on Neurotrophic Biomarkers and Cardiometabolic Parameters in Unmedicated Schizophrenia
- NCT number
- NCT03304457
- Status
- Completed
- Phases
- Phase 4
- Enrollment
- 100 participants, actual
- Lead sponsor
- All India Institute of Medical Sciences, Bhubaneswar
- Conditions
- Schizophrenia
- Interventions
- Olanzapine, Lurasidone
- First posted
- 2017-10-09
- Last updated
- 2020-03-31
Source ClinicalTrials.gov
Registered outcomes14
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Serum brain derived neurotrophic factor (BDNF) | 6 weeks | the change in serum level of BDNF from baseline after treatment with lurasidone or olanzapine |
| Secondary | serum nerve growth factor (NGF) | 6 weeks | the change in serum level of NGF from baseline after treatment with lurasidone or olanzapine |
| Secondary | Serum Neurotrophin 3 (NT3) | 6 weeks | the change in serum level of NT3 from baseline after treatment with lurasidone or olanzapine |
| Secondary | PANSS score | 6 weeks | To determine the association (if any) between change in serum neurotrophic factor and PANSS score |
| Secondary | Social and occupational functioning assessment scale (SOFAS) | 6 weeks | To determine the association (if any) between change in serum neurotrophic factor and SOFAS (Social and occupational functioning assessment scale) score |
| Secondary | Serum hsCRP | 6 weeks | to assess cardiovascular risk in schizophrenia |
| Secondary | Serum Insulin | 6 weeks | to assess insulin resistance |
| Secondary | LDL/HDL ratio | 6 weeks | to assess dyslipidemia and cardiovascular risk |
| Secondary | Fasting blood sugar | 6 weeks | to assess dysglycemia |
| Secondary | Glycosylated Hemoglobin (HbA1c) | 6 weeks | to assess dysglycemia |
1 to 10 of 14Source ClinicalTrials.gov
See all 14 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers14
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT03304457
GET https://conductscience.org/api/trials/v1/NCT03304457/registered