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Trial · NCT03326063

Outcomes15

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

TypeOutcomeTime framePopulationUnitsMeasured as
PRIMARYProvocative Dose 2 (PD2) During Aspirin Challenge6 weeks from screening visit ( at visit 2)mgMEAN
SECONDARYPercentage Change From Baseline of FEV1 During Aspirin Challenge (Bronchoconstriction)At Visit 2. The change in FEV1 from the morning baseline to the aspirin-induced lowest value in FEV1 during reaction to aspirin challenge later that same day.percentage change from baselineMEAN
SECONDARYAspirin-induced Leukotriene E4 (LTE4) LevelsVisit 2. The change in LTE4 levels from the morning baseline to the aspirin-induced highest value in LTE4 during reaction to aspirin challenge that same day.ng/mg creatinineMEAN
SECONDARYChange in Chronic Disease Control by Measurement of Lung Function Through FEV11 month (between Visit 1 and Visit 2)percent change from baselineMEAN
SECONDARYChange in Chronic Disease by Measurement of Asthma Control Through Asthma Control Questionnaire (ACQ) Score1 month (between Visit 1 and Visit 2)scores on a scaleMEAN
SECONDARYClinical Improvement of Chronic Disease - Sino-Nasal Outcome Test (SNOT-22) Score1 month (between Visit 1 and Visit 2)scores on a scaleMEAN
SECONDARYFractional Exhaled Nitric Oxide (FeNO)1 month (between Visit 1 and Visit 2)parts per billionMEAN
OTHER_PRE_SPECIFIEDPercent Change in Urinary Eicosanoid (TXB2 and LTE4) Levels1 month (between Visit 1 and Visit 2) and 6 weeks from screening visit ( at visit 2)
OTHER_PRE_SPECIFIEDNasal Eicosanoid Changes1 month (between Visit 1 and Visit 2) and 6 weeks from screening visit ( at visit 2)
OTHER_PRE_SPECIFIEDPlasma/Serum Tryptase Changes1 month (between Visit 1 and Visit 2) and 6 weeks from screening visit ( at visit 2)
OTHER_PRE_SPECIFIEDNasal Tryptase Changes1 month (between Visit 1 and Visit 2) and 6 weeks from screening visit ( at visit 2)
OTHER_PRE_SPECIFIEDPlatelet Activation - Numbers of Activated Platelets1 month (between Visit 1 and Visit 2) and during aspirin challenge visit
OTHER_PRE_SPECIFIEDPlatelet Activation - Percentages of Activated Platelets1 month (between Visit 1 and Visit 2) and 6 weeks from screening visit ( at visit 2)
OTHER_PRE_SPECIFIEDPlatelet Activation - Numbers of Platelet-leukocyte Aggregates1 month (between Visit 1 and Visit 2) and 6 weeks from screening visit ( at visit 2)
OTHER_PRE_SPECIFIEDPlatelet Activation - Percentages of Platelet-leukocyte Aggregates1 month (between Visit 1 and Visit 2) and 6 weeks from screening visit ( at visit 2)

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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