Short Chain Fatty Acid Metabolism in COPD
NCT03327181, Not applicable, Completed, Texas A&M University
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Short Chain Fatty Acid Metabolism in COPD | ClinicalTrials.gov |
| NCT number | NCT03327181 | ClinicalTrials.gov |
| Status | Completed | ClinicalTrials.gov |
| Phases | Not applicable | ClinicalTrials.gov |
| Enrollment | 63 participants, actual | ClinicalTrials.gov |
| Lead sponsor | Texas A&M University | ClinicalTrials.gov |
| Conditions | Chronic Obstructive Pulmonary Disease | ClinicalTrials.gov |
| Interventions | short chain fatty acid tracers | ClinicalTrials.gov |
| First posted | 2017-10-31 | ClinicalTrials.gov |
| Last updated | 2025-09-30 | ClinicalTrials.gov |
Registered outcomes 13
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | whole body short-chain fatty acid metabolism | -10, 2, 4, 6, 8, 10, 15, 20, 25, 30, 40, 50, 60 min | change in whole body scfa metabolism | ClinicalTrials.gov |
| Secondary | Fat free mass measured using dual-energy x-ray absorptiometry | 1 day | Difference in muscle mass between COPD patients and healthy older adults | ClinicalTrials.gov |
| Secondary | Fat mass measured using dual-energy x-ray absorptiometry | 1 day | Difference in fat mass between COPD patients and healthy older adults | ClinicalTrials.gov |
| Secondary | Bone density measured using dual-energy x-ray absorptiometry | 1 day | Difference in bone density between COPD patients and healthy older adults | ClinicalTrials.gov |
| Secondary | handgrip strength dynamometry | 1 day | Difference in handgrip strength between COPD patients and healthy older adults | ClinicalTrials.gov |
| Secondary | Micro-respiratory pressure meter measurement | 1 day | Difference in maximum inspiratory and expiratory pressure between COPD patients and healthy older adults | ClinicalTrials.gov |
| Secondary | moving balance platform measurement | 1 day | Changes in ability to maintain balance after perturbation of moving platform between COPD patients and healthy older adults. The maximum platform displacement the participant could withstand without stepping will be determined. | ClinicalTrials.gov |
| Secondary | Group differences in attention and executive functions as measured by Trail Making Test (TMT), | 1 day | In Part A, the examinee is instructed to connect a set of 25 circles with numbers as quickly as possible while maintaining accuracy. In Part B, the examinee is instructed to connect a set of 25 circles, alternating between numbers and letters, as quickly as possible while maintaining accuracy. Measures attentional resources and is a measure of the frontal lobe "executive" functions of visual search, set-switching and mental flexibility. The total time in seconds was reported for each measure. | ClinicalTrials.gov |
| Secondary | Group differences in attention and executive functions as measured by Stroop Color-Word Test (SCWT), | 1 day | a word page with words printed in black ink, a color page with blocks printed in color, and a color-word page where the color and the word do not match. The examinee reads the words or names the ink colors as quickly as possible within a time limit. Measures selective attention and inhibitory control. The total time in seconds was reported for each trial. | ClinicalTrials.gov |
| Secondary | Group differences in somatosensory functions as measured by vibrotactile behavioral battery | 1 day | The vibrotactile behavioral battery consists of a non-invasive set of brief tasks targeting sensory processes and inhibition. It can be used to detect neurobiological abnormalities in sensory processing. The battery of vibrotactile tasks involves the use of a small device that is designed to administer calibrated vibratory stimuli to the glabrous skin of digits 3 and 4 of the left hand and is connected to a laptop computer. | ClinicalTrials.gov |
| Secondary | Group differences in gut function as reported by "The Gastrointestinal Symptom Rating Scale" | 1 day | self-administered questionnaire regarding gut function and associated symptoms | ClinicalTrials.gov |
| Secondary | Group differences in physical activity as reported by "International Physical Activity Questionnaire" | 1 day | self-administered questionnaire regarding physical activity | ClinicalTrials.gov |
| Secondary | COPD Assessment Test | 1 day | self-administered questionnaire regarding impact of COPD on daily life | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 3
The papers the trial lists on ClinicalTrials.gov.
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 2
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| Stroop Color-Word Test | Secondary outcome | ConductCognition |
| Trail Making Test A | Secondary outcome | ConductCognition |
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)