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Trial · NCT03369236

Results by group31

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Change From Baseline In Composite Biopsy Score At Week 28Danicopan (Double-blind Treatment Period)Baseline11.7Standard Deviation 4.23score on a scale
Change From Baseline In Composite Biopsy Score At Week 28Placebo (Double-blind Treatment Period)Baseline9.3Standard Deviation 3.50score on a scale
Change From Baseline In Composite Biopsy Score At Week 28Danicopan (Double-blind Treatment Period)Week 289.2Standard Deviation 4.87score on a scale
Change From Baseline In Composite Biopsy Score At Week 28Placebo (Double-blind Treatment Period)Week 2810.7Standard Deviation 3.39score on a scale
Change From Baseline In Composite Biopsy Score At Week 28Danicopan (Double-blind Treatment Period)Change from Baseline-2.0Standard Deviation 1.87score on a scale
Change From Baseline In Composite Biopsy Score At Week 28Placebo (Double-blind Treatment Period)Change from Baseline1.3Standard Deviation 2.88score on a scale
Participants With Reduction In Proteinuria At Week 28Danicopan (Double-blind Treatment Period)0participants
Participants With Reduction In Proteinuria At Week 28Placebo (Double-blind Treatment Period)1participants
Change From Baseline In Proteinuria At Week 28Danicopan (Double-blind Treatment Period)Baseline6137.67Standard Deviation 2904.359mg/day
Change From Baseline In Proteinuria At Week 28Placebo (Double-blind Treatment Period)Baseline4274.47Standard Deviation 2992.819mg/day
Change From Baseline In Proteinuria At Week 28Danicopan (Double-blind Treatment Period)Week 285301.75Standard Deviation 2984.445mg/day
Change From Baseline In Proteinuria At Week 28Placebo (Double-blind Treatment Period)Week 285186.80Standard Deviation 4069.279mg/day
Change From Baseline In Proteinuria At Week 28Danicopan (Double-blind Treatment Period)Change from Baseline302.00Standard Deviation 764.211mg/day
Change From Baseline In Proteinuria At Week 28Placebo (Double-blind Treatment Period)Change from Baseline182.20Standard Deviation 994.558mg/day
Percent Change From Baseline In Proteinuria At Week 28Danicopan (Double-blind Treatment Period)12.5Standard Deviation 31.11percent change
Percent Change From Baseline In Proteinuria At Week 28Placebo (Double-blind Treatment Period)-10.4Standard Deviation 31.35percent change
Slope Of Estimated Glomerular Filtration Rate (eGFR) From Baseline To 6 MonthsDanicopan (Double-blind Treatment Period)-2.26840Standard Deviation 1.790814mL/min/1.73 m^2 per month
Slope Of Estimated Glomerular Filtration Rate (eGFR) From Baseline To 6 MonthsPlacebo (Double-blind Treatment Period)-1.45421Standard Deviation 2.228395mL/min/1.73 m^2 per month
Slope Of Estimated Glomerular Filtration Rate (eGFR) After Open-label Danicopan TreatmentDanicopan (Double-blind Treatment Period), Followed by Danicopan (Open-label Extension Period-1.02556Standard Deviation 1.389128mL/min/1.73 m^2 per month
Slope Of Estimated Glomerular Filtration Rate (eGFR) After Open-label Danicopan TreatmentPlacebo (Double-blind Treatment Period), Followed by Danicopan (Open-label Extension Period)-1.84935Standard Deviation 3.506810mL/min/1.73 m^2 per month

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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