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Trial · NCT03371355

Results by group212

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Percent Change From Baseline in Fasting Triglycerides Level at the Primary Analysis Time PointPooled Placebo-1695% Confidence Interval -29 to 0percent change
Percent Change From Baseline in Fasting Triglycerides Level at the Primary Analysis Time PointCohort B: ISIS 703802, 40 mg Q4W-3695% Confidence Interval -47 to -23percent change
Percent Change From Baseline in Fasting Triglycerides Level at the Primary Analysis Time PointCohort C: ISIS 703802, 80 mg Q4W-5395% Confidence Interval -60 to -43percent change
Percent Change From Baseline in Fasting Triglycerides Level at the Primary Analysis Time PointCohort A: ISIS 703802, 20 mg QW-4795% Confidence Interval -57 to -35percent change
Change From Baseline in Angiopoietin-Like 3 Protein at the Primary Analysis Time PointPooled Placebo6.7795% Confidence Interval -2.09 to 15.62μg/L
Change From Baseline in Angiopoietin-Like 3 Protein at the Primary Analysis Time PointCohort B: ISIS 703802, 40 mg Q4W-43.1195% Confidence Interval -52.27 to -33.94μg/L
Change From Baseline in Angiopoietin-Like 3 Protein at the Primary Analysis Time PointCohort C: ISIS 703802, 80 mg Q4W-64.8995% Confidence Interval -74.26 to -55.53μg/L
Change From Baseline in Angiopoietin-Like 3 Protein at the Primary Analysis Time PointCohort A: ISIS 703802, 20 mg QW-52.9895% Confidence Interval -63.99 to -41.96μg/L
Change From Baseline in TC, LDL-C, HDL-C, VLDL-C, Non-HDL-C, ApoB (ApoB-48, ApoB-100), ApoCIII, and ApoAI at the Primary Analysis Time PointPooled PlaceboTC-4.895% Confidence Interval -15.19 to 5.51mg/dL
Change From Baseline in TC, LDL-C, HDL-C, VLDL-C, Non-HDL-C, ApoB (ApoB-48, ApoB-100), ApoCIII, and ApoAI at the Primary Analysis Time PointCohort B: ISIS 703802, 40 mg Q4WTC-21.395% Confidence Interval -32.35 to -10.31mg/dL
Change From Baseline in TC, LDL-C, HDL-C, VLDL-C, Non-HDL-C, ApoB (ApoB-48, ApoB-100), ApoCIII, and ApoAI at the Primary Analysis Time PointCohort C: ISIS 703802, 80 mg Q4WTC-41.995% Confidence Interval -52.88 to -30.89mg/dL
Change From Baseline in TC, LDL-C, HDL-C, VLDL-C, Non-HDL-C, ApoB (ApoB-48, ApoB-100), ApoCIII, and ApoAI at the Primary Analysis Time PointCohort A: ISIS 703802, 20 mg QWTC-36.595% Confidence Interval -49.38 to -23.58mg/dL
Change From Baseline in TC, LDL-C, HDL-C, VLDL-C, Non-HDL-C, ApoB (ApoB-48, ApoB-100), ApoCIII, and ApoAI at the Primary Analysis Time PointPooled PlaceboLDL-C-2.595% Confidence Interval -11.21 to 6.14mg/dL
Change From Baseline in TC, LDL-C, HDL-C, VLDL-C, Non-HDL-C, ApoB (ApoB-48, ApoB-100), ApoCIII, and ApoAI at the Primary Analysis Time PointCohort B: ISIS 703802, 40 mg Q4WLDL-C5.095% Confidence Interval -4.78 to 14.70mg/dL
Change From Baseline in TC, LDL-C, HDL-C, VLDL-C, Non-HDL-C, ApoB (ApoB-48, ApoB-100), ApoCIII, and ApoAI at the Primary Analysis Time PointCohort C: ISIS 703802, 80 mg Q4WLDL-C-11.195% Confidence Interval -20.38 to -1.90mg/dL
Change From Baseline in TC, LDL-C, HDL-C, VLDL-C, Non-HDL-C, ApoB (ApoB-48, ApoB-100), ApoCIII, and ApoAI at the Primary Analysis Time PointCohort A: ISIS 703802, 20 mg QWLDL-C-11.395% Confidence Interval -21.76 to -0.84mg/dL
Change From Baseline in TC, LDL-C, HDL-C, VLDL-C, Non-HDL-C, ApoB (ApoB-48, ApoB-100), ApoCIII, and ApoAI at the Primary Analysis Time PointPooled PlaceboHDL-C2.295% Confidence Interval -0.38 to 4.69mg/dL
Change From Baseline in TC, LDL-C, HDL-C, VLDL-C, Non-HDL-C, ApoB (ApoB-48, ApoB-100), ApoCIII, and ApoAI at the Primary Analysis Time PointCohort B: ISIS 703802, 40 mg Q4WHDL-C-0.695% Confidence Interval -3.25 to 2.14mg/dL
Change From Baseline in TC, LDL-C, HDL-C, VLDL-C, Non-HDL-C, ApoB (ApoB-48, ApoB-100), ApoCIII, and ApoAI at the Primary Analysis Time PointCohort C: ISIS 703802, 80 mg Q4WHDL-C-6.495% Confidence Interval -9.13 to -3.77mg/dL
Change From Baseline in TC, LDL-C, HDL-C, VLDL-C, Non-HDL-C, ApoB (ApoB-48, ApoB-100), ApoCIII, and ApoAI at the Primary Analysis Time PointCohort A: ISIS 703802, 20 mg QWHDL-C-2.095% Confidence Interval -5.11 to 1.12mg/dL

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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GET https://conductscience.org/api/trials/v1/NCT03371355/results