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Trial · NCT03397121

Results by group16

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Percent Change in LDL-C From Baseline To Day 510Inclisiran-41.1595% Confidence Interval -44.52 to -37.77percent change
Percent Change in LDL-C From Baseline To Day 510Placebo8.3795% Confidence Interval 3.96 to 12.77percent change
Time-adjusted Percent Change in LDL-C From Baseline After Day 90 and up to Day 540Inclisiran-38.0895% Confidence Interval -41.03 to -35.14percent change
Time-adjusted Percent Change in LDL-C From Baseline After Day 90 and up to Day 540Placebo6.2295% Confidence Interval 3.26 to 9.17percent change
Absolute Change in LDL-C From Baseline to Day 510Inclisiran-58.9595% Confidence Interval -64.75 to -53.15mg/dL
Absolute Change in LDL-C From Baseline to Day 510Placebo9.9495% Confidence Interval 4.10 to 15.78mg/dL
Time-adjusted Absolute Change in LDL-C From Baseline After Day 90 and up to Day 540Inclisiran-56.5895% Confidence Interval -60.98 to -52.17mg/dL
Time-adjusted Absolute Change in LDL-C From Baseline After Day 90 and up to Day 540Placebo6.1795% Confidence Interval 1.72 to 10.62mg/dL
Percentage Change in Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) From Baseline to Day 510Inclisiran-60.6895% Confidence Interval -64.40 to -56.96percent change
Percentage Change in Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) From Baseline to Day 510Placebo17.6695% Confidence Interval 13.91 to 21.42percent change
Percentage Change in Total Cholesterol From Baseline to Day 510Inclisiran-25.1195% Confidence Interval -27.83 to -22.39percent change
Percentage Change in Total Cholesterol From Baseline to Day 510Placebo6.6695% Confidence Interval 3.96 to 9.36percent change
Percent Change in Apolipoprotein B (Apo-B) From Baseline To Day 510Inclisiran-33.1495% Confidence Interval -35.91 to -30.36percent change
Percent Change in Apolipoprotein B (Apo-B) From Baseline To Day 510Placebo2.9395% Confidence Interval 0.14 to 5.71percent change
Percent Change in Non-high-density Lipoprotein (HDL)-C From Baseline To Day 510Inclisiran-34.9395% Confidence Interval -38.46 to -31.40percent change
Percent Change in Non-high-density Lipoprotein (HDL)-C From Baseline To Day 510Placebo7.4395% Confidence Interval 3.93 to 10.92percent change

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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