Trial · NCT03441269
Adult Oral Ibuprofen Study for ED Pain Patients
NCT03441269, Phase 4, Completed, Antonios Likourezos; results first posted 2020-06-04
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Adult Oral Ibuprofen Study for ED Pain Patients. Trials, record NCT03441269. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03441269
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Adult Oral Ibuprofen Study for ED Pain Patients
- NCT number
- NCT03441269
- Status
- Completed
- Phases
- Phase 4
- Enrollment
- 225 participants, actual
- Lead sponsor
- Antonios Likourezos
- Conditions
- Pain, Acute
- Interventions
- Oral Ibuprofen
- First posted
- 2018-02-22
- Last updated
- 2020-06-04
- Results first posted
- 2020-06-04
Source ClinicalTrials.gov
Registered outcomes3
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Pain Reduction at 60 Minutes From Baseline of the 3 Oral Ibuprofen Groups | 60 minutes | Difference in mean pain scores among all groups from at 60 minutes from baseline; negative difference infers decrease in pain score. A pain score of 10 indicates severe pain, 5 indicates moderate pain and 0 indicates no pain. |
| Secondary | Rates of Adverse Event of the 3 Oral Ibuprofen Dosage Groups | 60 minutes | Rates of Adverse Event of the 3 Oral Ibuprofen Dosage Groups |
| Secondary | Rates of Requiring Rescue Analgesia | 60 minutes | Rates of Requiring Rescue Analgesia for pain management |
Source ClinicalTrials.gov
Outcomes3
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Pain Reduction at 60 Minutes From Baseline of the 3 Oral Ibuprofen Groups | 60 minutes | units on a scale | MEAN | |
| SECONDARY | Rates of Adverse Event of the 3 Oral Ibuprofen Dosage Groups | 60 minutes | Participants | COUNT_OF_PARTICIPANTS | |
| SECONDARY | Rates of Requiring Rescue Analgesia | 60 minutes | Participants | COUNT_OF_PARTICIPANTS |
Source ClinicalTrials.gov
Results by group9
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Pain Reduction at 60 Minutes From Baseline of the 3 Oral Ibuprofen Groups | 400mg/Dose | -2.12 | 95% Confidence Interval -2.45 to -1.80 | units on a scale | |
| Pain Reduction at 60 Minutes From Baseline of the 3 Oral Ibuprofen Groups | 600mg/Dose | -1.85 | 95% Confidence Interval -2.05 to -1.66 | units on a scale | |
| Pain Reduction at 60 Minutes From Baseline of the 3 Oral Ibuprofen Groups | 800mg/Dose | -1.96 | 95% Confidence Interval -2.18 to -1.74 | units on a scale | |
| Rates of Adverse Event of the 3 Oral Ibuprofen Dosage Groups | 400mg/Dose | 0 | Participants | ||
| Rates of Adverse Event of the 3 Oral Ibuprofen Dosage Groups | 600mg/Dose | 0 | Participants | ||
| Rates of Adverse Event of the 3 Oral Ibuprofen Dosage Groups | 800mg/Dose | 0 | Participants | ||
| Rates of Requiring Rescue Analgesia | 400mg/Dose | 0 | Participants | ||
| Rates of Requiring Rescue Analgesia | 600mg/Dose | 0 | Participants | ||
| Rates of Requiring Rescue Analgesia | 800mg/Dose | 0 | Participants |
Source ClinicalTrials.gov
Participant flow9
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | 400mg/Dose | 75 | |
| Overall Study | STARTED | 600mg/Dose | 75 | |
| Overall Study | STARTED | 800mg/Dose | 75 | |
| Overall Study | COMPLETED | 400mg/Dose | 75 | |
| Overall Study | COMPLETED | 600mg/Dose | 74 | |
| Overall Study | COMPLETED | 800mg/Dose | 74 | |
| Overall Study | NOT COMPLETED | 400mg/Dose | 0 | |
| Overall Study | NOT COMPLETED | 600mg/Dose | 1 | |
| Overall Study | NOT COMPLETED | 800mg/Dose | 1 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals9
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | 400mg/Dose | 0 | 75 |
| Total, all-cause mortality | 600mg/Dose | 0 | 74 |
| Total, all-cause mortality | 800mg/Dose | 0 | 74 |
| Total, other adverse events | 400mg/Dose | 0 | 75 |
| Total, other adverse events | 600mg/Dose | 0 | 74 |
| Total, other adverse events | 800mg/Dose | 0 | 74 |
| Total, serious adverse events | 400mg/Dose | 0 | 75 |
| Total, serious adverse events | 600mg/Dose | 0 | 74 |
| Total, serious adverse events | 800mg/Dose | 0 | 74 |
Source ClinicalTrials.gov
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 31383385 | DERIVED |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT03441269
GET https://conductscience.org/api/trials/v1/NCT03441269/registered