Trial · NCT03449095
Understanding Alcohol Reward in Social Context
NCT03449095, Not applicable, Completed, University of Illinois at Urbana-Champaign; results first posted 2024-07-31
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Understanding Alcohol Reward in Social Context. Trials, record NCT03449095. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03449095
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Understanding Alcohol Reward in Social Context
- NCT number
- NCT03449095
- Status
- Completed
- Phases
- Not applicable
- Enrollment
- 640 participants, actual
- Lead sponsor
- University of Illinois at Urbana-Champaign
- Conditions
- Alcohol Drinking, Alcohol Use Disorder, Alcohol Intoxication, Alcohol; Harmful Use, Alcoholism, Binge Drinking
- Interventions
- Alcohol
- First posted
- 2018-02-28
- Last updated
- 2024-07-31
- Results first posted
- 2024-07-31
Source ClinicalTrials.gov
Registered outcomes6
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Self-Reported Emotion | during the laboratory session, up to 9 hours | Positive and negative emotion will be assessed during the laboratory beverage-administration session via self-report on the "8-item Mood Measure." This measure yields two subscales (positive emotion; negative emotion) each ranges from 1 to 6. For positive mood, higher value represents increased alcohol reward. For negative mood, lower value represents increased alcohol reward. |
| Primary | Self-Reported Social Reinforcement | during the laboratory session, up to 9 hours | Social reinforcement will be assessed using an index of perceived social closeness as well as a modified version of the Perceived Group Reinforcement Scale. The score of the scale ranges from 1 to 9. Higher score indicates increased alcohol reward. |
| Secondary | Social Bonding | 1 day (laboratory session) | Social bonding will be assessed during the laboratory beverage-administration session. This will be assessed by examining the synchronization among group members of facial expressions of emotion. |
| Secondary | Self-Reported Emotion | 2-3 week ambulatory assessment period | Positive and negative emotion will be assessed during the ambulatory assessment period via self-report on the "8-item Mood Measure." |
| Secondary | Interpersonal Distance | 1 day (laboratory session) | Physical proximity to other participants during the experiment |
| Secondary | Neuro-cognitive Social Engagement | 1 day (laboratory session) | Electroencephalogram (EEG) hyperscanning methods will be employed to assess task engagement and social attention, including through the examination of event-related potentials (ERPs) during social tasks. |
Source ClinicalTrials.gov
Outcomes6
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Self-Reported Emotion | during the laboratory session, up to 9 hours | score on a scale | MEAN | |
| PRIMARY | Self-Reported Social Reinforcement | during the laboratory session, up to 9 hours | score on a scale | MEAN | |
| SECONDARY | Social Bonding | 1 day (laboratory session) | |||
| SECONDARY | Self-Reported Emotion | 2-3 week ambulatory assessment period | |||
| SECONDARY | Interpersonal Distance | 1 day (laboratory session) | |||
| SECONDARY | Neuro-cognitive Social Engagement | 1 day (laboratory session) |
Source ClinicalTrials.gov
Results by group6
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Self-Reported Emotion | Alcohol Administration | Positive Emotion | 3.49 | Standard Deviation 1.085 | score on a scale |
| Self-Reported Emotion | Control Beverage Administration | Positive Emotion | 2.98 | Standard Deviation 1.101 | score on a scale |
| Self-Reported Emotion | Alcohol Administration | Negative Emotion | 0.32 | Standard Deviation 0.447 | score on a scale |
| Self-Reported Emotion | Control Beverage Administration | Negative Emotion | 0.673 | Standard Deviation 0.750 | score on a scale |
| Self-Reported Social Reinforcement | Alcohol Administration | 7.471 | Standard Deviation 1.129 | score on a scale | |
| Self-Reported Social Reinforcement | Control Beverage Administration | 7.180 | Standard Deviation 1.155 | score on a scale |
Source ClinicalTrials.gov
Participant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Alcohol Administration | 320 | |
| Overall Study | STARTED | Control Beverage Administration | 320 | |
| Overall Study | COMPLETED | Alcohol Administration | 320 | |
| Overall Study | COMPLETED | Control Beverage Administration | 320 | |
| Overall Study | NOT COMPLETED | Alcohol Administration | 0 | |
| Overall Study | NOT COMPLETED | Control Beverage Administration | 0 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Alcohol Administration | 0 | 320 |
| Total, all-cause mortality | Control Beverage Administration | 0 | 320 |
| Total, other adverse events | Alcohol Administration | 0 | 320 |
| Total, other adverse events | Control Beverage Administration | 0 | 320 |
| Total, serious adverse events | Alcohol Administration | 0 | 320 |
| Total, serious adverse events | Control Beverage Administration | 0 | 320 |
Source ClinicalTrials.gov
Papers5
The papers the trial lists on ClinicalTrials.gov.
Grants1
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years |
|---|---|---|---|---|---|
| R01AA025969 | Examining the Impact of Stress on the Emotionally Reinforcing Properties of Alcohol in Heavy Social Drinkers: A Multimodal Investigation Integrating Laboratory and Ambulatory Methods | FAIRBAIRN, CATHARINE | UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN | NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM | 2017 to 2025 |
Source NIH RePORTER
Trial comparisons2
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|---|
| Alcohol Administration vs Control Beverage Administration: deaths from any cause | Trial comparisons |
| Alcohol Administration vs Control Beverage Administration: serious adverse events | Trial comparisons |
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT03449095
GET https://conductscience.org/api/trials/v1/NCT03449095/registered