Registered outcomes11

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

1 to 11 of 11

List	Outcome	Time frame
Primary	Phase Ia- Maximum tolerated dose (MTD) based on number of patients with dose limiting toxicities (DLTs) during first treatment cycle	Up to 28 days
Primary	Phase Ib - Progression-free survival	Up to 24 months
Primary	Phase Ia - Number of patients with DLTs during first treatment cycle (21 days, Arm A; 28 days, Arm B)	Up to 28 days
Primary	Phase Ib - Number of patients with DLTs during the first treatment cycle	Up to 28 days
Secondary	Phase Ia - Cmax: Maximum measured concentration of BI 907828 in plasma	Up to 24 months
Secondary	Phase Ia - AUC0-∞: Area under the concentration-time curve in plasma over the time interval from 0 extrapolated to infinity	Up to 24 months
Secondary	Phase Ib - Objective response	Up to 24 months
Secondary	Phase Ib - Overall survival	Up to 24 months
Secondary	Phase Ib - Number of patients with Grade ≥3 treatment-related adverse events observed during the entire treatment period	Up to 24 months
Secondary	Phase Ib - Cmax: Maximum measured concentration of BI 907828 in plasma	Up to 24 months
Secondary	Phase Ib - AUC0-∞: Area under the concentration-time curve in plasma over the time interval from 0 extrapolated to infinity	Up to 24 months

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
ClinicalTrials.govNo license stated
NIH RePORTER's clinical studies and project filesPublic domain

Each source's terms

ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
ClinicalTrials.govnone stated
NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Twenty rows a page, as JSON. No key.

GET https://conductscience.org/api/trials/v1/NCT03449381/registered