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Trial · NCT03449446

Results by group21

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Percentage of Participants Experiencing Treatment-Emergent Adverse Events (TEAEs)Selonsertib84.6percentage of participants
Percentage of Participants Experiencing Treatment-Emergent Adverse Events (TEAEs)Firsocostat85.0percentage of participants
Percentage of Participants Experiencing Treatment-Emergent Adverse Events (TEAEs)Cilofexor92.5percentage of participants
Percentage of Participants Experiencing Treatment-Emergent Adverse Events (TEAEs)SEL + FIR88.6percentage of participants
Percentage of Participants Experiencing Treatment-Emergent Adverse Events (TEAEs)SEL + CILO96.1percentage of participants
Percentage of Participants Experiencing Treatment-Emergent Adverse Events (TEAEs)FIR + CILO91.0percentage of participants
Percentage of Participants Experiencing Treatment-Emergent Adverse Events (TEAEs)Placebo79.5percentage of participants
Percentage of Participants Experiencing Treatment-Emergent Laboratory AbnormalitiesSelonsertib94.9percentage of participants
Percentage of Participants Experiencing Treatment-Emergent Laboratory AbnormalitiesFirsocostat100.0percentage of participants
Percentage of Participants Experiencing Treatment-Emergent Laboratory AbnormalitiesCilofexor97.5percentage of participants
Percentage of Participants Experiencing Treatment-Emergent Laboratory AbnormalitiesSEL + FIR98.7percentage of participants
Percentage of Participants Experiencing Treatment-Emergent Laboratory AbnormalitiesSEL + CILO96.1percentage of participants
Percentage of Participants Experiencing Treatment-Emergent Laboratory AbnormalitiesFIR + CILO100.0percentage of participants
Percentage of Participants Experiencing Treatment-Emergent Laboratory AbnormalitiesPlacebo94.9percentage of participants
Percentage of Participants Who Achieved a ≥ 1-Stage Improvement in Fibrosis Without Worsening of NASH at Week 48Selonsertib28.695% Confidence Interval 3.7 to 71.0percentage of participants
Percentage of Participants Who Achieved a ≥ 1-Stage Improvement in Fibrosis Without Worsening of NASH at Week 48Firsocostat12.195% Confidence Interval 3.4 to 28.2percentage of participants
Percentage of Participants Who Achieved a ≥ 1-Stage Improvement in Fibrosis Without Worsening of NASH at Week 48Cilofexor11.895% Confidence Interval 3.3 to 27.5percentage of participants
Percentage of Participants Who Achieved a ≥ 1-Stage Improvement in Fibrosis Without Worsening of NASH at Week 48SEL + FIR15.595% Confidence Interval 8.0 to 26.0percentage of participants
Percentage of Participants Who Achieved a ≥ 1-Stage Improvement in Fibrosis Without Worsening of NASH at Week 48SEL + CILO19.195% Confidence Interval 10.6 to 30.5percentage of participants
Percentage of Participants Who Achieved a ≥ 1-Stage Improvement in Fibrosis Without Worsening of NASH at Week 48FIR + CILO20.995% Confidence Interval 11.9 to 32.6percentage of participants

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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