Trial · NCT03451734
Optimizing and Individualizing the Pharmacological Treatment of First-episode Schizophrenic Patients
NCT03451734, Completed, Central South University
3 sourcestrials-2026-11-12-0.4.0
Cite this record
ConductScience Library. Optimizing and Individualizing the Pharmacological Treatment of First-episode Schizophrenic Patients. Trials, record NCT03451734. Release trials-2026-11-12-0.4.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03451734
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Optimizing and Individualizing the Pharmacological Treatment of First-episode Schizophrenic Patients
- NCT number
- NCT03451734
- Status
- Completed
- Enrollment
- 2,000 participants, actual
- Lead sponsor
- Central South University
- Conditions
- Schizophrenia, Metabolic Syndrome
- Interventions
- antipsychotic medications, adjunctive group, metformin and lifestyle intervention
- First posted
- 2018-03-02
- Last updated
- 2021-08-12
Source ClinicalTrials.gov
Registered outcomes4
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Positive And Negative Syndrome Scale (PANSS) | 8 weeks | The change of Positive And Negative Syndrome Scale (PANSS) total, positive and negative symptoms before and after treatment at different follow up point. |
| Primary | Clinical Global Impressions(CGI) | 8 weeks | The change of Clinical Global Impressions(CGI):severity of illness(SI), global improvement(GI) and efficacy index(EI) before and after treatment at different follow up point. |
| Primary | Global Assessment Function(GAF) | 8 weeks | The change of Global Assessment Function(GAF) before and after treatment at different follow up point. |
| Primary | MATRICS Consensus Cognitive Battery (MCCB) composite score | 8 weeks | The investigators will use the MATRICS Consensus Cognitive Battery (MCCB) Composite score as primary cognitive outcome measure before and after treatment at different follow up point. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers8
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT03451734
GET https://conductscience.org/api/trials/v1/NCT03451734/registered