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Trial · NCT03452228

Results by group170

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Percent Change From Baseline in Fasting Triglycerides (TG) Level Following 12 Weeks of Repeated IV Doses of Evinacumab in Actual Cohort 3 ParticipantsActual Cohort 3: DB Placebo/SB Evinacumab IV 15mg/kg Q4W19.2Standard Error 99.1Percent Change
Percent Change From Baseline in Fasting Triglycerides (TG) Level Following 12 Weeks of Repeated IV Doses of Evinacumab in Actual Cohort 3 ParticipantsActual Cohort 3: DB Evinacumab/SB Evinacumab IV 15mg/kg Q4W-37.2Standard Error 42.9Percent Change
Percent Change From Baseline in Fasting TG Level Following 2 to 24 Weeks of Repeated IV Doses of Evinacumab Overall GroupPlacebo Q4W (DBTP)Percent change at Week 21.99Standard Deviation 45.687Percent Change
Percent Change From Baseline in Fasting TG Level Following 2 to 24 Weeks of Repeated IV Doses of Evinacumab Overall GroupEvinacumab IV 15mg/kg Q4W (DBTP)Percent change at Week 2-51.38Standard Deviation 33.160Percent Change
Percent Change From Baseline in Fasting TG Level Following 2 to 24 Weeks of Repeated IV Doses of Evinacumab Overall GroupPlacebo Q4W (DBTP)Percent change at Week 4-3.52Standard Deviation 41.029Percent Change
Percent Change From Baseline in Fasting TG Level Following 2 to 24 Weeks of Repeated IV Doses of Evinacumab Overall GroupEvinacumab IV 15mg/kg Q4W (DBTP)Percent change at Week 4-43.70Standard Deviation 39.119Percent Change
Percent Change From Baseline in Fasting TG Level Following 2 to 24 Weeks of Repeated IV Doses of Evinacumab Overall GroupPlacebo Q4W (DBTP)Percent change at Week 692.56Standard Deviation 262.368Percent Change
Percent Change From Baseline in Fasting TG Level Following 2 to 24 Weeks of Repeated IV Doses of Evinacumab Overall GroupEvinacumab IV 15mg/kg Q4W (DBTP)Percent change at Week 6-52.69Standard Deviation 40.214Percent Change
Percent Change From Baseline in Fasting TG Level Following 2 to 24 Weeks of Repeated IV Doses of Evinacumab Overall GroupPlacebo Q4W (DBTP)Percent change at Week 84.83Standard Deviation 38.941Percent Change
Percent Change From Baseline in Fasting TG Level Following 2 to 24 Weeks of Repeated IV Doses of Evinacumab Overall GroupEvinacumab IV 15mg/kg Q4W (DBTP)Percent change at Week 8-32.86Standard Deviation 64.787Percent Change
Percent Change From Baseline in Fasting TG Level Following 2 to 24 Weeks of Repeated IV Doses of Evinacumab Overall GroupPlacebo Q4W (DBTP)Percent change at Week 1217.47Standard Deviation 47.610Percent Change
Percent Change From Baseline in Fasting TG Level Following 2 to 24 Weeks of Repeated IV Doses of Evinacumab Overall GroupEvinacumab IV 15mg/kg Q4W (DBTP)Percent change at Week 12-42.03Standard Deviation 61.086Percent Change
Percent Change From Baseline in Fasting TG Level Following 2 to 24 Weeks of Repeated IV Doses of Evinacumab Overall GroupEvinacumab IV 15mg/kg Q4W (SBTP)Percent change at Week 16-39.23Standard Deviation 46.026Percent Change
Percent Change From Baseline in Fasting TG Level Following 2 to 24 Weeks of Repeated IV Doses of Evinacumab Overall GroupEvinacumab IV 15mg/kg Q4W (SBTP)Percent change at Week 20-38.09Standard Deviation 49.070Percent Change
Percent Change From Baseline in Fasting TG Level Following 2 to 24 Weeks of Repeated IV Doses of Evinacumab Overall GroupEvinacumab IV 15mg/kg Q4W (SBTP)Percent change at Week 24-35.86Standard Deviation 65.011Percent Change
Percent Change From Baseline in Fasting TG Level Following 2 to 24 Weeks of Repeated IV Doses of Evinacumab in Actual Cohorts 1, 2, and 3Actual Cohort 1: DB Evinacumab/SB Evinacumab IV 15mg/kg Q4WPercent change at Week 2-28.3Inter-Quartile Range -40.3 to -6.5Percent Change
Percent Change From Baseline in Fasting TG Level Following 2 to 24 Weeks of Repeated IV Doses of Evinacumab in Actual Cohorts 1, 2, and 3Actual Cohort 2: DB Evinacumab/SB Evinacumab IV 15mg/kg Q4WPercent change at Week 2-77.5Inter-Quartile Range -81.2 to -58.9Percent Change
Percent Change From Baseline in Fasting TG Level Following 2 to 24 Weeks of Repeated IV Doses of Evinacumab in Actual Cohorts 1, 2, and 3Actual Cohort 3: DB Evinacumab/SB Evinacumab IV 15mg/kg Q4WPercent change at Week 2-74.4Inter-Quartile Range -84.2 to -37.1Percent Change
Percent Change From Baseline in Fasting TG Level Following 2 to 24 Weeks of Repeated IV Doses of Evinacumab in Actual Cohorts 1, 2, and 3Actual Cohort 1: DB Evinacumab/SB Evinacumab IV 15mg/kg Q4WPercent change at Week 4-19.0Inter-Quartile Range -69.6 to -2.7Percent Change
Percent Change From Baseline in Fasting TG Level Following 2 to 24 Weeks of Repeated IV Doses of Evinacumab in Actual Cohorts 1, 2, and 3Actual Cohort 2: DB Evinacumab/SB Evinacumab IV 15mg/kg Q4WPercent change at Week 4-48.0Inter-Quartile Range -76.2 to -29.2Percent Change

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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