Trial · NCT03478774

Physiology Regarding Apnoeic Oxygenation During Nasal Cannula Therapy at Different Flow Rates

NCT03478774, Not applicable, Completed, Insel Gruppe AG, University Hospital Bern

3 sourcestrials-2026-11-12-0.5.0

Cite this record

ConductScience Library. Physiology Regarding Apnoeic Oxygenation During Nasal Cannula Therapy at Different Flow Rates. Trials, record NCT03478774. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03478774

On this page

Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title: Physiology Regarding Apnoeic Oxygenation During Nasal Cannula Therapy at Different Flow Rates
NCT number: NCT03478774
Status: Completed
Phases: Not applicable
Enrollment: 125 participants, actual
Lead sponsor: Insel Gruppe AG, University Hospital Bern
Conditions: Apnoeic Oxygenation
Interventions: Oxygen 70l/min, Oxygen 10 l/min, Oxygen 2l/min, Jaw thrust, Videolaryngoscopy, oxygen 0.25l/min
First posted: 2018-03-27
Last updated: 2021-02-03

Source ClinicalTrials.gov

Registered outcomes18

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

List	Outcome	Time frame	Description
Primary	pCO2 increase in kPa/min	15 or 30 minutes (maximum apnea time)	pCO2 will be measured transcutaneously throughout the apnea period
Secondary	Lowest Saturation	During apnea period (until end-point is met or max. 15 or 30 minutes)	Lowest SpO2 in %
Secondary	Change in PaO2 in kPa	During apnea period (until end-point is met or max. 15 or 30 minutes)	Blood gas analyses as well as transcutaneous measurement
Secondary	Change in cardiac output in L/min	During apnea period (until end-point is met or max. 15 or 30 minutes)	Cardiac output will be measured using pulse pressure measurement
Secondary	Change in cerebral perfusion in %	During apnea period (until end-point is met or max. 15 or 30 minutes)	Near infrared spectroscopy will be measured continuously
Secondary	Changes in end-expiratory lung impedance	During apnoea time (until end-point is met or max. 15 or 30 minutes)	To quantify atelectasis during apnoeic oxygenation
Secondary	Change in invasive blood pressure	During apnoea time (until end-point is met or max. 15 or 30 minutes)	Measurement of change due to hypercarbia
Secondary	Standard monitoring	During apnoea time (until end-point is met or max. 15 or 30 minutes)	3 pole ECG
Secondary	Depth of anaesthesia	During apnoea time (until end-point is met or max. 15 or 30 minutes)	Using Narcotrend-EEG
Secondary	Bilateral brain oxygenation	During apnoea time (until end-point is met or max. 15 or 30 minutes)	Using NIRS

1 to 10 of 18Source ClinicalTrials.gov

See all 18 registered outcomes

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers5

The papers the trial lists on ClinicalTrials.gov.

PMID	Listed as	Source
25388828	BACKGROUND	PubMed
28403407	BACKGROUND	PubMed
31300494	DERIVED	PubMed
36170281	DERIVED	PubMed
37262066	DERIVED	PubMed

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov: 2026-11-12; ClinicalTrials.gov
Results, from AACT: 2026-03-23; AACT
NIH grant links: 2026-11-13; NIH RePORTER

Sources 3

ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
ClinicalTrials.govNo license stated
NIH RePORTER's clinical studies and project filesPublic domain

Each source's terms

ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
ClinicalTrials.govnone stated
NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT03478774

GET https://conductscience.org/api/trials/v1/NCT03478774/registered

API reference For AI assistants