Trial · NCT03488108

Platelet Rich Plasma Versus Minoxidil Foam for Treatment of Androgenic Alopecia in Women

NCT03488108, Phase 1, Phase 2, Completed, Mayo Clinic; results first posted 2020-04-08

3 sourcestrials-2026-11-12-0.5.0

Cite this record

ConductScience Library. Platelet Rich Plasma Versus Minoxidil Foam for Treatment of Androgenic Alopecia in Women. Trials, record NCT03488108. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03488108

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title: Platelet Rich Plasma Versus Minoxidil Foam for Treatment of Androgenic Alopecia in Women
NCT number: NCT03488108
Status: Completed
Phases: Phase 1, Phase 2
Enrollment: 20 participants, actual
Lead sponsor: Mayo Clinic
Conditions: Alopecia
Interventions: Platelet Rich Plasma, Minoxidil Foam
First posted: 2018-04-04
Last updated: 2020-04-08
Results first posted: 2020-04-08

Source ClinicalTrials.gov

Registered outcomes6

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

List	Outcome	Time frame	Description
Primary	Change in Hair Count	baseline, after 12 weeks of treatment	Phototrichograms of all scalps performed using FotoFinder video-epiluminescence microscopy (FotoFinder Systems GmbH) in combination with TrichoScan digital image analysis (TRICHOLOG GmbH and DatInf mbH). The percent change in the total number of hairs per 0.65 cm2 was measured after both interventions, in each Arm/Group.
Primary	Change in Vellus Hair Density	baseline, after 12 weeks of treatment	Phototrichograms of all scalps performed using FotoFinder video-epiluminescence microscopy (FotoFinder Systems GmbH) in combination with TrichoScan digital image analysis (TRICHOLOG GmbH and DatInf mbH). The percent change in the total number of vellus hairs per cm2 was measured after both interventions, in each Arm/Group.
Primary	Change in Terminal Hair Density	baseline, after 12 weeks of treatment	Phototrichograms of all scalps performed using FotoFinder video-epiluminescence microscopy (FotoFinder Systems GmbH) in combination with TrichoScan digital image analysis (TRICHOLOG GmbH and DatInf mbH). The percent change in the total number of Terminal hairs per cm2 was measured after both interventions, in each Arm/Group.
Primary	Change in Cumulative Thickness	baseline, after 12 weeks of treatment	Phototrichograms of all scalps performed using FotoFinder video-epiluminescence microscopy (FotoFinder Systems GmbH) in combination with TrichoScan digital image analysis (TRICHOLOG GmbH and DatInf mbH). The percent change in the total sum of thickness of each hair was measured after both interventions, in each Arm/Group.
Secondary	Adverse Event of Swelling on Scalp	after 12 weeks of treatment	Total number of participants experiencing swelling on scalp was measured after both interventions, in each Arm/Group.
Secondary	Adverse Event of Redness on Scalp	after 12 weeks of treatment	Total number of participants experiencing Redness on Scalp was measured after both interventions, in each Arm/Group.

Source ClinicalTrials.gov

Outcomes6

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

Type	Outcome	Time frame	Population	Units	Measured as
PRIMARY	Change in Hair Count	baseline, after 12 weeks of treatment	One subject dropped out of the study after received PRP treatment only. This subject is included in results information regarding PRP only.	percent change	MEDIAN
PRIMARY	Change in Vellus Hair Density	baseline, after 12 weeks of treatment	One subject dropped out of the study after received PRP treatment only. This subject is included in results information regarding PRP only.	percent change	MEDIAN
PRIMARY	Change in Terminal Hair Density	baseline, after 12 weeks of treatment	One subject dropped out of the study after received PRP treatment only. This subject is included in results information regarding PRP only.	percent change	MEDIAN
PRIMARY	Change in Cumulative Thickness	baseline, after 12 weeks of treatment	One subject dropped out of the study after received PRP treatment only. This subject is included in results information regarding PRP only.	percent change	MEDIAN
SECONDARY	Adverse Event of Swelling on Scalp	after 12 weeks of treatment		Participants	COUNT_OF_PARTICIPANTS
SECONDARY	Adverse Event of Redness on Scalp	after 12 weeks of treatment		Participants	COUNT_OF_PARTICIPANTS

Source ClinicalTrials.gov

Results by group12

Each measurement the trial posted, group by group, in the words and numbers it posted.

Outcome	Group	Value	Spread	Units
Change in Hair Count	Platelet Rich Plasma	7.7	Inter-Quartile Range -7.2 to 17.9	percent change
Change in Hair Count	Minoxidil Foam	22.7	Inter-Quartile Range -18.0 to 59.0	percent change
Change in Vellus Hair Density	Platelet Rich Plasma	25.7	Inter-Quartile Range -37.6 to 121.3	percent change
Change in Vellus Hair Density	Minoxidil Foam	18.6	Inter-Quartile Range -29.4 to 166.5	percent change
Change in Terminal Hair Density	Platelet Rich Plasma	-0.7	Inter-Quartile Range -49.5 to 27.6	percent change
Change in Terminal Hair Density	Minoxidil Foam	12.8	Inter-Quartile Range -19.4 to 119.4	percent change
Change in Cumulative Thickness	Platelet Rich Plasma	-3.5	Inter-Quartile Range -14.1 to 32.2	percent change
Change in Cumulative Thickness	Minoxidil Foam	20.6	Inter-Quartile Range -21.3 to 83.3	percent change
Adverse Event of Swelling on Scalp	Platelet Rich Plasma	0		Participants
Adverse Event of Swelling on Scalp	Minoxidil Foam	0		Participants

1 to 10 of 12Source ClinicalTrials.gov

See all 12 results by group

Participant flow18

How many started, completed or left each group, period by period.

Period	Milestone	Group	Participants
First Intervention (12 Weeks)	STARTED	Platelet Rich Plasma First, Then Minoxidil Foam	10
First Intervention (12 Weeks)	STARTED	Minoxidil Foam First, Then Platelet Rich Plasma	10
First Intervention (12 Weeks)	COMPLETED	Platelet Rich Plasma First, Then Minoxidil Foam	10
First Intervention (12 Weeks)	COMPLETED	Minoxidil Foam First, Then Platelet Rich Plasma	9
First Intervention (12 Weeks)	NOT COMPLETED	Platelet Rich Plasma First, Then Minoxidil Foam	0
First Intervention (12 Weeks)	NOT COMPLETED	Minoxidil Foam First, Then Platelet Rich Plasma	1
Washout (2 Months)	STARTED	Platelet Rich Plasma First, Then Minoxidil Foam	10
Washout (2 Months)	STARTED	Minoxidil Foam First, Then Platelet Rich Plasma	9
Washout (2 Months)	COMPLETED	Platelet Rich Plasma First, Then Minoxidil Foam	10
Washout (2 Months)	COMPLETED	Minoxidil Foam First, Then Platelet Rich Plasma	9

1 to 10 of 18Source ClinicalTrials.gov

See all 18 participant flow

Adverse events6

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

Type	Event	Organ system	Group	Affected	At risk	Events
other	Pain	General disorders	Platelet Rich Plasma	2	19	2
other	Pain	General disorders	Minoxidil Foam	0	18	0
other	Itching	Skin and subcutaneous tissue disorders	Platelet Rich Plasma	1	19	1
other	Itching	Skin and subcutaneous tissue disorders	Minoxidil Foam	0	18	0
other	Bruising	Skin and subcutaneous tissue disorders	Platelet Rich Plasma	0	19	0
other	Bruising	Skin and subcutaneous tissue disorders	Minoxidil Foam	1	18	1

Source ClinicalTrials.gov

Adverse event totals6

The totals the trial posted for each group.

Total	Group	Affected	At risk
Total, all-cause mortality	Platelet Rich Plasma	0	19
Total, all-cause mortality	Minoxidil Foam	0	18
Total, other adverse events	Platelet Rich Plasma	3	19
Total, other adverse events	Minoxidil Foam	1	18
Total, serious adverse events	Platelet Rich Plasma	0	19
Total, serious adverse events	Minoxidil Foam	0	18

Source ClinicalTrials.gov

Papers1

The papers the trial lists on ClinicalTrials.gov.

PMID	Listed as
31574029	DERIVED

Source PubMed

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons4

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

Comparison	Source
Platelet Rich Plasma vs Minoxidil Foam: Adverse Event of Swelling on Scalp	Trial comparisons
Platelet Rich Plasma vs Minoxidil Foam: Adverse Event of Redness on Scalp	Trial comparisons
Platelet Rich Plasma vs Minoxidil Foam: deaths from any cause	Trial comparisons
Platelet Rich Plasma vs Minoxidil Foam: serious adverse events	Trial comparisons

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov: 2026-11-12; ClinicalTrials.gov
Results, from AACT: 2026-03-23; AACT
NIH grant links: 2026-11-13; NIH RePORTER

Sources 3

ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
ClinicalTrials.govNo license stated
NIH RePORTER's clinical studies and project filesPublic domain

Each source's terms

ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
ClinicalTrials.govnone stated
NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT03488108

GET https://conductscience.org/api/trials/v1/NCT03488108/registered

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