Trial · NCT03490019
Treatment of Bardet-Biedl-Syndrome With Metformin for Evaluation of a Possible Visual Improvement
NCT03490019, Phase 2, Withdrawn, University Hospital Tuebingen
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Treatment of Bardet-Biedl-Syndrome With Metformin for Evaluation of a Possible Visual Improvement. Trials, record NCT03490019. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03490019
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Treatment of Bardet-Biedl-Syndrome With Metformin for Evaluation of a Possible Visual Improvement
- NCT number
- NCT03490019
- Status
- Withdrawn
- Phases
- Phase 2
- Enrollment
- 0 participants, actual
- Lead sponsor
- University Hospital Tuebingen
- Conditions
- Bardet-Biedl Syndrome, Visual Impairment
- Interventions
- Metformin
- First posted
- 2018-04-06
- Last updated
- 2019-04-18
Source ClinicalTrials.gov
Registered outcomes12
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Visual acuity | Baseline to day 210 | Course of visual acuity according to appropriate table |
| Secondary | Number of letters read | Baseline to day 210 | Course visual acuity defined as number of letters read |
| Secondary | Results of Static perimetry | Baseline to day 210 | Course of results of static perimetry given by measurement of light contrast sensitivity within at least 5 central points. |
| Secondary | Results of Kinetic perimetry | Baseline to day 210 | Course of results of kinetic perimetry given by mapping the visual field sensitivity boundaries using Goldmann perimetry |
| Secondary | Electroretinogram (ERG) dim-flash | Baseline to day 210 | Course of values of ERG dim-flash |
| Secondary | Electroretinogram (ERG) standard flash | Baseline to day 210 | Course of values of ERG standard flash at 3 ods/m2 |
| Secondary | Electroretinogram (ERG) cone-single-flash | Baseline to day 210 | Course of values of ERG cone-single-flash at 30cd/m2 |
| Secondary | Electroretinogram (ERG) 30-Hz-Flicker | Baseline to day 210 | Course of values of ERG measured by 30-Hz-Flicker in all patients |
| Secondary | Visual evoked potential (VEP) - amplitude | Baseline to day 210 | Course of results of measurement of VEP amplitude |
| Secondary | Visual evoked potential (VEP) - latency time | Baseline to day 210 | Course of results of measurement of VEP latency time |
1 to 10 of 12Source ClinicalTrials.gov
See all 12 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT03490019
GET https://conductscience.org/api/trials/v1/NCT03490019/registered