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Trial · NCT03500549

Results by group137

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Least Squares (LS) Mean Change From Baseline to Week 16 in Hemoglobin (Hb) Level During the RCPPegcetacoplan to Pegcetacoplan2.37Standard Error 0.363Grams per deciliter (g/dL)
Least Squares (LS) Mean Change From Baseline to Week 16 in Hemoglobin (Hb) Level During the RCPEculizumab to Pegcetacoplan-1.47Standard Error 0.666Grams per deciliter (g/dL)
Percentage of Subjects Who Did Not Require a Transfusion (Transfusion Avoidance) During the RCPPegcetacoplan to Pegcetacoplan85.4Percentage of subjects
Percentage of Subjects Who Did Not Require a Transfusion (Transfusion Avoidance) During the RCPEculizumab to Pegcetacoplan15.4Percentage of subjects
LS Mean Change From Baseline to Week 16 in Absolute Reticulocyte Count (ARC) During the RCPPegcetacoplan to Pegcetacoplan-135.82Standard Error 6.54310^9 cells/ liter (L)
LS Mean Change From Baseline to Week 16 in Absolute Reticulocyte Count (ARC) During the RCPEculizumab to Pegcetacoplan27.79Standard Error 11.85910^9 cells/ liter (L)
LS Mean Change From Baseline to Week 16 in Lactate Dehydrogenase (LDH) Level During the RCPPegcetacoplan to Pegcetacoplan-14.76Standard Error 42.708Units (U)/L
LS Mean Change From Baseline to Week 16 in Lactate Dehydrogenase (LDH) Level During the RCPEculizumab to Pegcetacoplan-10.12Standard Error 71.025Units (U)/L
LS Mean Change From Baseline to Week 16 in Functional Assessment of Chronic Illness Therapy (FACIT) - Fatigue Scale Score During the RCPPegcetacoplan to Pegcetacoplan9.22Standard Error 1.607Score on a scale
LS Mean Change From Baseline to Week 16 in Functional Assessment of Chronic Illness Therapy (FACIT) - Fatigue Scale Score During the RCPEculizumab to Pegcetacoplan-2.65Standard Error 2.821Score on a scale
Percentage of Subjects Who Achieved a Hb Response in the Absence of Transfusions at Week 16Pegcetacoplan to Pegcetacoplan75.6Percentage of subjects
Percentage of Subjects Who Achieved a Hb Response in the Absence of Transfusions at Week 16Eculizumab to Pegcetacoplan0.0Percentage of subjects
Percentage of Subjects Who Achieved Reticulocyte Normalization in the Absence of Transfusions at Week 16Pegcetacoplan to Pegcetacoplan78.0Percentage of subjects
Percentage of Subjects Who Achieved Reticulocyte Normalization in the Absence of Transfusions at Week 16Eculizumab to Pegcetacoplan2.6Percentage of subjects
Percentage of Subjects Who Achieved Hb Normalization in the Absence of Transfusions at Week 16Pegcetacoplan to Pegcetacoplan34.1Percentage of subjects
Percentage of Subjects Who Achieved Hb Normalization in the Absence of Transfusions at Week 16Eculizumab to Pegcetacoplan0.0Percentage of subjects
LS Mean Change From Baseline to Week 16 in Indirect Bilirubin Level During the RCPPegcetacoplan to Pegcetacoplan-17.78Standard Error 2.727Micromole (μmol)/L
LS Mean Change From Baseline to Week 16 in Indirect Bilirubin Level During the RCPEculizumab to Pegcetacoplan4.15Standard Error 4.477Micromole (μmol)/L
LS Mean Change From Baseline to Week 16 in Haptoglobin Level During the RCPPegcetacoplan to Pegcetacoplan-0.02Standard Error 0.033g/L
LS Mean Change From Baseline to Week 16 in Haptoglobin Level During the RCPEculizumab to Pegcetacoplan0.12Standard Error 0.063g/L

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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