Trial · NCT03509168
The Efficacy and Safety of Preoperative Misoprostol in Blood-loss Reduction During Myomectomy.
NCT03509168, Phase 2, Phase 3, Unknown, Makerere University
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. The Efficacy and Safety of Preoperative Misoprostol in Blood-loss Reduction During Myomectomy. Trials, record NCT03509168. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03509168
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- The Efficacy and Safety of Preoperative Misoprostol in Blood-loss Reduction During Myomectomy.
- NCT number
- NCT03509168
- Status
- Unknown
- Phases
- Phase 2, Phase 3
- Enrollment
- 46 participants, estimated
- Lead sponsor
- Makerere University
- Conditions
- Uterine Fibroid
- Interventions
- Misoprostol Pfizer Brand, Non-insertion of Misoprostol Pfizer Brand
- First posted
- 2018-04-26
- Last updated
- 2018-04-30
Source ClinicalTrials.gov
Registered outcomes6
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | intraoperative blood loss during open myomectomy in milliliters | immediate post-operative | Soaked mops will be weighed and blood loss estimated by subtracting the soaked weight from the dry weight and by multiplying this by 1.060 (average density of human blood is 1.06g/ml); a volume in ml would be acquired. Only mops are intended to be routinely used during the operation for cleaning and clearing the operation field although measurement of blood collected in the suction cylinder in milliliters if used will also be added. Adequate mops will be provided to avoid any spillage onto the operating table polythene sheet. A standardized digital weighing scale will be availed in each operating room. Any spillage onto the bed, however, will be collected in a polythene sheet and poured into a measuring cylinder for quantification. |
| Secondary | duration of surgery | immediate postoperative | from incision time to time for insertion of last stitch |
| Secondary | duration of hospital stay | 4th postoperative day. (96 hours) | number of days spent within the hospital post-operatively |
| Secondary | need for blood transfusion | during and within 72 hours after open myomectomy | hemodynamic instability during and after open myomectomy following profuse hemorrhage as assessed by the clinicians. |
| Secondary | Serious adverse outcomes | 72 hours following open myomectomy | death, massive transfusion \>5 units of blood, development of deep venous thrombosis pulmonary edema and pulmonary embolism |
| Secondary | drop in postoperative hemoglobin concentration | hemoglobin estimation done approximately 72 hours post-operatively | Hemoglobin estimation done both pre- and post-operatively; difference between the two values to be a measure of amount of blood lost. patients that receive blood transfusion to be excluded. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT03509168
GET https://conductscience.org/api/trials/v1/NCT03509168/registered