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Trial · NCT03511105

Results by group206

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Baseline Adjusted Total Protein Concentration in Broncho-alveolar (BAL) Samples at 24 Hours After Segmental LPS Challenge (26 Hours Post-first Dose)Placebo348.4695% Confidence Interval 285.97 to 425.67Milligrams per liter
Baseline Adjusted Total Protein Concentration in Broncho-alveolar (BAL) Samples at 24 Hours After Segmental LPS Challenge (26 Hours Post-first Dose)GSK2798745318.4395% Confidence Interval 260.18 to 389.98Milligrams per liter
Baseline Adjusted Total Cell Count of Neutrophils in BAL Samples at 24 Hours After Segmental LPS Challenge (26 Hours Post-first Dose)Placebo58.9495% Confidence Interval 42.70 to 81.4210^6 cells per milliliter
Baseline Adjusted Total Cell Count of Neutrophils in BAL Samples at 24 Hours After Segmental LPS Challenge (26 Hours Post-first Dose)GSK279874554.6395% Confidence Interval 39.21 to 75.9010^6 cells per milliliter
Baseline Adjusted Differential Cell Count of Neutrophils in BAL Samples at 24 Hours After Segmental LPS Challenge (26 Hours Post-first Dose)Placebo58.5795% Confidence Interval 54.37 to 63.09Percentage of total cell count
Baseline Adjusted Differential Cell Count of Neutrophils in BAL Samples at 24 Hours After Segmental LPS Challenge (26 Hours Post-first Dose)GSK279874558.5495% Confidence Interval 54.22 to 63.12Percentage of total cell count
Number of Participants Reporting Serious Adverse Events (SAEs) and Non-SAEsPlaceboAny SAE0Participants
Number of Participants Reporting Serious Adverse Events (SAEs) and Non-SAEsGSK2798745Any SAE0Participants
Number of Participants Reporting Serious Adverse Events (SAEs) and Non-SAEsPlaceboAny non-SAE10Participants
Number of Participants Reporting Serious Adverse Events (SAEs) and Non-SAEsGSK2798745Any non-SAE7Participants
Change From Baseline Values for Clinical Chemistry ParametersPlaceboALP, Day 21.64Standard Deviation 8.144International units per liter
Change From Baseline Values for Clinical Chemistry ParametersGSK2798745ALP, Day 24.00Standard Deviation 7.578International units per liter
Change From Baseline Values for Clinical Chemistry ParametersPlaceboALP, Day 9-3.20Standard Deviation 7.953International units per liter
Change From Baseline Values for Clinical Chemistry ParametersGSK2798745ALP, Day 9-1.86Standard Deviation 6.198International units per liter
Change From Baseline Values for Clinical Chemistry ParametersPlaceboALT, Day 21.2Standard Deviation 16.87International units per liter
Change From Baseline Values for Clinical Chemistry ParametersGSK2798745ALT, Day 2-3.5Standard Deviation 3.08International units per liter
Change From Baseline Values for Clinical Chemistry ParametersPlaceboALT, Day 94.4Standard Deviation 26.94International units per liter
Change From Baseline Values for Clinical Chemistry ParametersGSK2798745ALT, Day 9-2.6Standard Deviation 5.14International units per liter
Change From Baseline Values for Clinical Chemistry ParametersPlaceboAST, Day 218.4Standard Deviation 109.78International units per liter
Change From Baseline Values for Clinical Chemistry ParametersGSK2798745AST, Day 2-2.3Standard Deviation 3.97International units per liter

Source ClinicalTrials.govtrials-2026-11-12-0.4.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNone stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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