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Trial · NCT03514420

Results by group63

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Percent Change From Baseline in Fasting Triglycerides Levels at End of the Treatment (Week 27)AKCEA-ANGPTL3-LRx 20 mg-59.9Standard Deviation 26.29percent change
Change From Baseline in Area Under the Curve (AUC) of Plasma Glucose as Assessed by Mixed Meal Test (MMT) at End of the TreatmentAKCEA-ANGPTL3-LRx 20 mg-9815.0Standard Deviation 4071.43mg/dL*min
Change From Baseline in AUC of Serum Insulin as Assessed by MMT at End of the TreatmentAKCEA-ANGPTL3-LRx 20 mg3262.0Standard Deviation 3775.09milli international units per liter*min
Change From Baseline in AUC of Serum C-peptide as Assessed by MMT at End of the TreatmentAKCEA-ANGPTL3-LRx 20 mg-192.3Standard Deviation 257.10ng/mL*min
Change From Baseline in AUC of Free Fatty Acid (FFA) as Assessed by MMT at End of the TreatmentAKCEA-ANGPTL3-LRx 20 mg-60.0Standard Deviation 42.52mEq/L*min
Change From Baseline in AUC of Serum Ghrelin as Assessed by MMT at End of the TreatmentAKCEA-ANGPTL3-LRx 20 mg8479.5Standard Deviation 7241.20pg/mL*min
Change From Baseline in AUC of Incretin Hormone (Gastric Inhibitory Polypeptide [GIP]) as Assessed by MMT at End of the TreatmentAKCEA-ANGPTL3-LRx 20 mg-1694.7Standard Deviation 11752.50pg/mL*min
Change From Baseline in AUC of Incretin Hormone (Glucagon-like Peptide -1 [GLP-1]) as Assessed by MMT at End of the TreatmentAKCEA-ANGPTL3-LRx 20 mg1677.3Standard Deviation 11301.79pmol/L*min
Change From Baseline in AUC of Peptide Tyrosine Tyrosine (PYY) as Assessed by MMT at End of the TreatmentAKCEA-ANGPTL3-LRx 20 mg6549.0Standard Deviation 10632.50pg/mL*min
Change From Baseline in HDL-C at End of the TreatmentAKCEA-ANGPTL3-LRx 20 mg2.1Standard Deviation 6.88mg/dL
Change From Baseline in LDL-C at End of the TreatmentAKCEA-ANGPTL3-LRx 20 mg24.0Standard Deviation NAmg/dL
Change From Baseline in Total Cholesterol (TC) at End of the TreatmentAKCEA-ANGPTL3-LRx 20 mg-42.3Standard Deviation 32.29mg/dL
Change From Baseline in VLDL-C at End of the TreatmentAKCEA-ANGPTL3-LRx 20 mg-32.0Standard Deviation NAmg/dL
Change From Baseline in Non-HDL-C at End of the TreatmentAKCEA-ANGPTL3-LRx 20 mg-44.4Standard Deviation 34.27mg/dL
Change From Baseline in ApoB at End of the TreatmentAKCEA-ANGPTL3-LRx 20 mg1.25Standard Deviation 25.265mg/dL
Change From Baseline in ApoB-48 at End of the TreatmentAKCEA-ANGPTL3-LRx 20 mg-3.601Standard Deviation 1.3284mg/dL
Change From Baseline in Apolipoprotein B 100 (ApoB-100) at End of the TreatmentAKCEA-ANGPTL3-LRx 20 mg4.433Standard Deviation 24.6001mg/dL
Change From Baseline in ApoA-1 at End of the TreatmentAKCEA-ANGPTL3-LRx 20 mg-20.8Standard Deviation 22.92mg/dL
Change From Baseline in ApoC-III at End of the TreatmentAKCEA-ANGPTL3-LRx 20 mg-13.555Standard Deviation 9.1220mg/dL
Change From Baseline in ApoC-III: LDL at End of the TreatmentAKCEA-ANGPTL3-LRx 20 mg-2.110Standard Deviation NAmg/dL

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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