Trial · NCT03541447
Tolvaptan-Octreotide LAR Combination in ADPKD
NCT03541447, Phase 2, Completed, Mario Negri Institute for Pharmacological Research
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Tolvaptan-Octreotide LAR Combination in ADPKD. Trials, record NCT03541447. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03541447
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Tolvaptan-Octreotide LAR Combination in ADPKD
- NCT number
- NCT03541447
- Status
- Completed
- Phases
- Phase 2
- Enrollment
- 20 participants, actual
- Lead sponsor
- Mario Negri Institute for Pharmacological Research
- Conditions
- Autosomal Dominant Polycystic Kidney Disease
- Interventions
- Tolvaptan, Octreotide LAR, Placebo
- First posted
- 2018-05-30
- Last updated
- 2022-11-03
- Other registries' IDs
- eudract:2017-004701-40
Source ClinicalTrials.gov
Registered outcomes2
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Glomerular Filtration Rate (GFR) | Changes from 4 weeks before randomization at baseline, 1,4,8,9,12 and 16 weeks after the randomization. | GFR will be assessed by the Iohexol Plasma Clearance Technique |
| Secondary | Total Kidney Volume (TKV) | Changes from baseline at 4,8,12 and 16 weeks after the randomization. | TKV will be assessed by Magnetic Resonance Imaging (MRI) |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers2
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT03541447
GET https://conductscience.org/api/trials/v1/NCT03541447/registered