Trial · NCT03568175
A Study of JR-141 in Patients With Mucopolysaccharidosis II
NCT03568175, Phase 2, Phase 3, Completed, JCR Pharmaceuticals Co., Ltd.
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. A Study of JR-141 in Patients With Mucopolysaccharidosis II. Trials, record NCT03568175. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03568175
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- A Study of JR-141 in Patients With Mucopolysaccharidosis II
- NCT number
- NCT03568175
- Status
- Completed
- Phases
- Phase 2, Phase 3
- Enrollment
- 28 participants, actual
- Lead sponsor
- JCR Pharmaceuticals Co., Ltd.
- Conditions
- Mucopolysaccharidosis II
- Interventions
- JR-141
- First posted
- 2018-06-26
- Last updated
- 2022-11-14
Source ClinicalTrials.gov
Registered outcomes15
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change From Baseline in Heparan Sulfate Levels in Cerebrospinal Fluid | Baseline to 52 weeks | |
| Secondary | Change From Baseline in Serum Heparan Sulfate Levels. | Baseline, 24-26 weeks, 50-52 weeks | |
| Secondary | Change From Baseline in Serum Dermatan Sulfate Levels. | Baseline, 24-26 weeks, 50-52 weeks | |
| Secondary | Change From Baseline in Urinary Heparan Sulfate Levels. | Baseline, 25 weeks, 52 weeks | |
| Secondary | Change From Baseline in Urinary Dermatan Sulfate Levels. | Baseline, 25 weeks, 52 weeks | |
| Secondary | Change From Baseline in Liver Volumes. | Baseline, 25 weeks, 52 weeks | |
| Secondary | Change From Baseline in Spleen Volumes. | Baseline, 25 weeks, 52 weeks | |
| Secondary | Change From Baseline in Cardiac Function. | Baseline, 25 weeks, 52 weeks | |
| Secondary | Change From Baseline in 6-minute Walk Test Distance. | Baseline, 25 weeks, 52 weeks | Item 9 will be administrated only in patients judged by the investigator or subinvestigator to be possible to perform the 6-minutes walk test |
| Secondary | Change From Baseline in Joint Range of Motion. | Baseline, 25 weeks, 52 weeks |
1 to 10 of 15Source ClinicalTrials.gov
See all 15 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT03568175
GET https://conductscience.org/api/trials/v1/NCT03568175/registered